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Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways.
Bellia F, Lanza V, García-Viñuales S, Ahmed IMM, Pietropaolo A, Iacobucci C, Malgieri G, D'Abrosca G, Fattorusso R, Nicoletti VG, Sbardella D, Tundo GR, Coletta M, Pirone L, Pedone E, Calcagno D, Grasso G, Milardi D. Bellia F, et al. Chem Sci. 2019 Jan 10;10(9):2732-2742. doi: 10.1039/c8sc03394c. eCollection 2019 Mar 7. Chem Sci. 2019. PMID: 30996991 Free PMC article.
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity.
Santoro AM, Lanza V, Bellia F, Sbardella D, Tundo GR, Cannizzo A, Grasso G, Arizzi M, Nicoletti VG, Alcaro S, Costa G, Pietropaolo A, Malgieri G, D'Abrosca G, Fattorusso R, García-Viñuales S, Ahmed IMM, Coletta M, Milardi D. Santoro AM, et al. Among authors: bellia f. ChemMedChem. 2020 Feb 5;15(3):302-316. doi: 10.1002/cmdc.201900612. Epub 2019 Dec 17. ChemMedChem. 2020. PMID: 31797568
Neuroprotective Effect of Carnosine Is Mediated by Insulin-Degrading Enzyme.
Distefano A, Caruso G, Oliveri V, Bellia F, Sbardella D, Zingale GA, Caraci F, Grasso G. Distefano A, et al. Among authors: bellia f. ACS Chem Neurosci. 2022 May 18;13(10):1588-1593. doi: 10.1021/acschemneuro.2c00201. Epub 2022 Apr 26. ACS Chem Neurosci. 2022. PMID: 35471926 Free PMC article.
85 results