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Riproximin is a recently discovered type II ribosome inactivating protein with potential for treating cancer.
Biotechnol Adv. 2014 Nov 1;32(6):1077-90. doi: 10.1016/j.biotechadv.2014.03.008. Epub 2014 Mar 31.
Biotechnol Adv. 2014.
PMID: 24699434
Review.
The expression of genes contributing to pancreatic adenocarcinoma progression is influenced by the respective environment.
Sagini MN, Zepp M, Bergmann F, Bozza M, Harbottle R, Berger MR.
Sagini MN, et al.
Genes Cancer. 2018 Mar;9(3-4):114-129. doi: 10.18632/genesandcancer.173.
Genes Cancer. 2018.
PMID: 30108682
Free PMC article.
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Lactosyl-sepharose binding proteins from pancreatic cancer cells show differential expression in primary and metastatic organs.
Sagini MN, Klika KD, Hotz-Wagenblatt A, Zepp M, Berger MR.
Sagini MN, et al.
Exp Biol Med (Maywood). 2020 Apr;245(7):631-643. doi: 10.1177/1535370220910691. Epub 2020 Mar 4.
Exp Biol Med (Maywood). 2020.
PMID: 32131629
Free PMC article.
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A subgroup of lactosyl-Sepharose binding proteins requires calcium for affinity and galactose for anti-proliferation.
Sagini MN, Hotz-Wagenblatt A, Berger MR.
Sagini MN, et al.
Chem Biol Interact. 2021 Jan 25;334:109354. doi: 10.1016/j.cbi.2020.109354. Epub 2020 Dec 10.
Chem Biol Interact. 2021.
PMID: 33309620
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Riproximin Exhibits Diversity in Sugar Binding, and Modulates some Metastasis-Related Proteins with Lectin like Properties in Pancreatic Ductal Adenocarcinoma.
Sagini MN, Klika KD, Orry A, Zepp M, Mutiso J, Berger MR.
Sagini MN, et al.
Front Pharmacol. 2020 Nov 30;11:549804. doi: 10.3389/fphar.2020.549804. eCollection 2020.
Front Pharmacol. 2020.
PMID: 33328982
Free PMC article.
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Khasianine Affects the Expression of Sugar-Sensitive Proteins in Pancreatic Cancer Cells, Which Are Altered in Data from the Rat Model and Patients.
Sagini MN, Klika KD, Owen RW, Berger MR.
Sagini MN, et al.
ACS Pharmacol Transl Sci. 2023 Apr 13;6(5):727-737. doi: 10.1021/acsptsci.3c00013. eCollection 2023 May 12.
ACS Pharmacol Transl Sci. 2023.
PMID: 37200805
Free PMC article.
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EPI-X4, a CXCR4 antagonist inhibits tumor growth in pancreatic cancer and lymphoma models.
Sagini MN, Zepp M, Eyol E, Ali DM, Gromova S, Dahlmann M, Behrens D, Groeschel C, Tischmeier L, Hoffmann J, Berger MR, Forssmann WG.
Sagini MN, et al.
Peptides. 2024 May;175:171111. doi: 10.1016/j.peptides.2023.171111. Epub 2023 Nov 28.
Peptides. 2024.
PMID: 38036098
Free article.
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