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Phosphoinositide-mediated oligomerization of a defensin induces cell lysis.
Poon IKh, Baxter AA, Lay FT, Mills GD, Adda CG, Payne JA, Phan TK, Ryan GF, White JA, Veneer PK, van der Weerden NL, Anderson MA, Kvansakul M, Hulett MD. Poon IKh, et al. Among authors: ryan gf. Elife. 2014 Apr 1;3:e01808. doi: 10.7554/eLife.01808. Elife. 2014. PMID: 24692446 Free PMC article.
The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity.
Santavanond JP, Chiu YH, Tixeira R, Liu Z, Yap JKY, Chen KW, Li CL, Lu YR, Roncero-Carol J, Hoijman E, Rutter SF, Shi B, Ryan GF, Hodge AL, Caruso S, Baxter AA, Ozkocak DC, Johnson C, Day ZI, Mayfosh AJ, Hulett MD, Phan TK, Atkin-Smith GK, Poon IKH. Santavanond JP, et al. Among authors: ryan gf. Cell Death Dis. 2024 Feb 9;15(2):123. doi: 10.1038/s41419-024-06513-z. Cell Death Dis. 2024. PMID: 38336804 Free PMC article.
Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial.
Gao Y, Weenink B, van den Bent MJ, Erdem-Eraslan L, Kros JM, Sillevis Smitt P, Hoang-Xuan K, Brandes AA, Vos M, Dhermain F, Enting R, Ryan GF, Chinot O, Ben Hassel M, van Linde ME, Mason WP, Gijtenbeek JMM, Balana C, von Deimling A, Gorlia T, Stupp R, Hegi ME, Baumert BG, French PJ. Gao Y, et al. Among authors: ryan gf. Eur J Cancer. 2018 May;94:168-178. doi: 10.1016/j.ejca.2018.02.023. Epub 2018 Mar 20. Eur J Cancer. 2018. PMID: 29571083 Clinical Trial.
Author reply: To PMID 23157521.
Ling IT, Siew TK, Loh NK, Ryan GF. Ling IT, et al. Among authors: ryan gf. Intern Med J. 2013 Jul;43(7):842-3. doi: 10.1111/imj.12192. Intern Med J. 2013. PMID: 23841772 No abstract available.
40 results