Lythgoe K - Search Results

1

Virulence and pathogenesis of HIV-1 infection: an evolutionary perspective.

Fraser C, Lythgoe K, Leventhal GE, Shirreff G, Hollingsworth TD, Alizon S, Bonhoeffer S. Fraser C, et al. Among authors: lythgoe k. Science. 2014 Mar 21;343(6177):1243727. doi: 10.1126/science.1243727. Science. 2014. PMID: 24653038 Free PMC article. Review.

2

New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levels.

Lythgoe KA, Fraser C. Lythgoe KA, et al. Proc Biol Sci. 2012 Aug 22;279(1741):3367-75. doi: 10.1098/rspb.2012.0595. Epub 2012 May 16. Proc Biol Sci. 2012. PMID: 22593106 Free PMC article.

3

Is HIV short-sighted? Insights from a multistrain nested model.

Lythgoe KA, Pellis L, Fraser C. Lythgoe KA, et al. Evolution. 2013 Oct;67(10):2769-82. doi: 10.1111/evo.12166. Epub 2013 Jun 13. Evolution. 2013. PMID: 24094332 Free PMC article.

4

Large Variations in HIV-1 Viral Load Explained by Shifting-Mosaic Metapopulation Dynamics.

Lythgoe KA, Blanquart F, Pellis L, Fraser C. Lythgoe KA, et al. PLoS Biol. 2016 Oct 5;14(10):e1002567. doi: 10.1371/journal.pbio.1002567. eCollection 2016 Oct. PLoS Biol. 2016. PMID: 27706164 Free PMC article.

5

A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in Uganda.

Blanquart F, Grabowski MK, Herbeck J, Nalugoda F, Serwadda D, Eller MA, Robb ML, Gray R, Kigozi G, Laeyendecker O, Lythgoe KA, Nakigozi G, Quinn TC, Reynolds SJ, Wawer MJ, Fraser C. Blanquart F, et al. Elife. 2016 Nov 5;5:e20492. doi: 10.7554/eLife.20492. Elife. 2016. PMID: 27815945 Free PMC article.

6

Effect of the Latent Reservoir on the Evolution of HIV at the Within- and Between-Host Levels.

Doekes HM, Fraser C, Lythgoe KA. Doekes HM, et al. PLoS Comput Biol. 2017 Jan 19;13(1):e1005228. doi: 10.1371/journal.pcbi.1005228. eCollection 2017 Jan. PLoS Comput Biol. 2017. PMID: 28103248 Free PMC article.

7

Evolution of HIV-1 within untreated individuals and at the population scale in Uganda.

Raghwani J, Redd AD, Longosz AF, Wu CH, Serwadda D, Martens C, Kagaayi J, Sewankambo N, Porcella SF, Grabowski MK, Quinn TC, Eller MA, Eller LA, Wabwire-Mangen F, Robb ML, Fraser C, Lythgoe KA. Raghwani J, et al. Among authors: lythgoe ka. PLoS Pathog. 2018 Jul 27;14(7):e1007167. doi: 10.1371/journal.ppat.1007167. eCollection 2018 Jul. PLoS Pathog. 2018. PMID: 30052678 Free PMC article.

8

Link between the numbers of particles and variants founding new HIV-1 infections depends on the timing of transmission.

Thompson RN, Wymant C, Spriggs RA, Raghwani J, Fraser C, Lythgoe KA. Thompson RN, et al. Virus Evol. 2019 Jan 30;5(1):vey038. doi: 10.1093/ve/vey038. eCollection 2019 Jan. Virus Evol. 2019. PMID: 30723550 Free PMC article.

9

Number of HIV-1 founder variants is determined by the recency of the source partner infection.

Villabona-Arenas CJ, Hall M, Lythgoe KA, Gaffney SG, Regoes RR, Hué S, Atkins KE. Villabona-Arenas CJ, et al. Science. 2020 Jul 3;369(6499):103-108. doi: 10.1126/science.aba5443. Science. 2020. PMID: 32631894 Free PMC article.

10

Time to evaluate COVID-19 contact-tracing apps.

Colizza V, Grill E, Mikolajczyk R, Cattuto C, Kucharski A, Riley S, Kendall M, Lythgoe K, Bonsall D, Wymant C, Abeler-Dörner L, Ferretti L, Fraser C. Colizza V, et al. Among authors: lythgoe k. Nat Med. 2021 Mar;27(3):361-362. doi: 10.1038/s41591-021-01236-6. Nat Med. 2021. PMID: 33589822 No abstract available.

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