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Properties and synthesis of 2-{2-fluoro (or bromo)-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low membrane permeabilizing and gastric lesion-producing activities.
Yamakawa N, Suemasu S, Matoyama M, Kimoto A, Takeda M, Tanaka K, Ishihara T, Katsu T, Okamoto Y, Otsuka M, Mizushima T. Yamakawa N, et al. Among authors: mizushima t. J Med Chem. 2010 Nov 11;53(21):7879-82. doi: 10.1021/jm101116s. J Med Chem. 2010. PMID: 20954731
Synthesis and biological evaluation of loxoprofen derivatives.
Yamakawa N, Suemasu S, Matoyama M, Tanaka K, Katsu T, Miyata K, Okamoto Y, Otsuka M, Mizushima T. Yamakawa N, et al. Among authors: mizushima t. Bioorg Med Chem. 2011 Jun 1;19(11):3299-311. doi: 10.1016/j.bmc.2011.04.050. Epub 2011 May 1. Bioorg Med Chem. 2011. PMID: 21570308
Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities.
Yamashita Y, Tanaka K, Asano T, Yamakawa N, Kobayashi D, Ishihara T, Hanaya K, Shoji M, Sugai T, Wada M, Mashimo T, Fukunishi Y, Mizushima T. Yamashita Y, et al. Among authors: mizushima t. Bioorg Med Chem. 2014 Jul 1;22(13):3488-97. doi: 10.1016/j.bmc.2014.04.029. Epub 2014 Apr 30. Bioorg Med Chem. 2014. PMID: 24844758
Membrane permeabilization by non-steroidal anti-inflammatory drugs.
Tomisato W, Tanaka K, Katsu T, Kakuta H, Sasaki K, Tsutsumi S, Hoshino T, Aburaya M, Li D, Tsuchiya T, Suzuki K, Yokomizo K, Mizushima T. Tomisato W, et al. Among authors: mizushima t. Biochem Biophys Res Commun. 2004 Oct 22;323(3):1032-9. doi: 10.1016/j.bbrc.2004.08.205. Biochem Biophys Res Commun. 2004. PMID: 15381103
1,005 results