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Drug discovery in renal disease--towards a more efficient framework.
Miyata T, Ando T, Hiragi H, Watanabe K, Yamamoto F, Vaughan DE, Kurokawa T, Oshima Y, van Ypersele de Strihou C, Takeuchi M. Miyata T, et al. Among authors: vaughan de. Nat Rev Nephrol. 2014 May;10(5):290-6. doi: 10.1038/nrneph.2014.36. Epub 2014 Mar 18. Nat Rev Nephrol. 2014. PMID: 24642801 Review.
A small molecule inhibitor to plasminogen activator inhibitor 1 inhibits macrophage migration.
Ichimura A, Matsumoto S, Suzuki S, Dan T, Yamaki S, Sato Y, Kiyomoto H, Ishii N, Okada K, Matsuo O, Hou FF, Vaughan DE, van Ypersele de Strihou C, Miyata T. Ichimura A, et al. Among authors: vaughan de. Arterioscler Thromb Vasc Biol. 2013 May;33(5):935-42. doi: 10.1161/ATVBAHA.113.301224. Epub 2013 Mar 7. Arterioscler Thromb Vasc Biol. 2013. PMID: 23471233
PAI-1 contributes to homocysteine-induced cellular senescence.
Sun T, Ghosh AK, Eren M, Miyata T, Vaughan DE. Sun T, et al. Among authors: vaughan de. Cell Signal. 2019 Dec;64:109394. doi: 10.1016/j.cellsig.2019.109394. Epub 2019 Aug 28. Cell Signal. 2019. PMID: 31472244 Free PMC article.
PAI-1 is a critical regulator of FGF23 homeostasis.
Eren M, Place AT, Thomas PM, Flevaris P, Miyata T, Vaughan DE. Eren M, et al. Among authors: vaughan de. Sci Adv. 2017 Sep 13;3(9):e1603259. doi: 10.1126/sciadv.1603259. eCollection 2017 Sep. Sci Adv. 2017. PMID: 28924605 Free PMC article.
Nitric oxide prevents alveolar senescence and emphysema in a mouse model.
Boe AE, Eren M, Morales-Nebreda L, Murphy SB, Budinger GR, Mutlu GM, Miyata T, Vaughan DE. Boe AE, et al. Among authors: vaughan de. PLoS One. 2015 Mar 10;10(3):e0116504. doi: 10.1371/journal.pone.0116504. eCollection 2015. PLoS One. 2015. PMID: 25756287 Free PMC article.
256 results