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Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter.
Porée B, Kypriotou M, Chadjichristos C, Beauchef G, Renard E, Legendre F, Melin M, Gueret S, Hartmann DJ, Malléin-Gerin F, Pujol JP, Boumediene K, Galéra P. Porée B, et al. J Biol Chem. 2008 Feb 22;283(8):4850-65. doi: 10.1074/jbc.M706387200. Epub 2007 Dec 7. J Biol Chem. 2008. PMID: 18065760 Free article.
[Human chondrocyte responsiveness to bone morphogenetic protein-2 after their in vitro dedifferentiation: potential use of bone morphogenetic protein-2 for cartilage cell therapy].
Salentey V, Claus S, Bougault C, Paumier A, Aubert-Foucher E, Perrier-Groult E, Ronzière MC, Freyria AM, Galéra P, Beauchef G, Duterque-Coquillaud M, Piperno M, Damour O, Herbage B, Mallein-Gerin F. Salentey V, et al. Pathol Biol (Paris). 2009 Jun;57(4):282-9. doi: 10.1016/j.patbio.2008.04.013. Epub 2008 Jun 6. Pathol Biol (Paris). 2009. PMID: 18538953 French.
Cartilage-characteristic matrix reconstruction by sequential addition of soluble factors during expansion of human articular chondrocytes and their cultivation in collagen sponges.
Claus S, Mayer N, Aubert-Foucher E, Chajra H, Perrier-Groult E, Lafont J, Piperno M, Damour O, Mallein-Gerin F. Claus S, et al. Tissue Eng Part C Methods. 2012 Feb;18(2):104-12. doi: 10.1089/ten.tec.2011.0259. Epub 2011 Nov 14. Tissue Eng Part C Methods. 2012. PMID: 21933021
81 results