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Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.
Warren TK, Wells J, Panchal RG, Stuthman KS, Garza NL, Van Tongeren SA, Dong L, Retterer CJ, Eaton BP, Pegoraro G, Honnold S, Bantia S, Kotian P, Chen X, Taubenheim BR, Welch LS, Minning DM, Babu YS, Sheridan WP, Bavari S. Warren TK, et al. Nature. 2014 Apr 17;508(7496):402-5. doi: 10.1038/nature13027. Epub 2014 Mar 2. Nature. 2014. PMID: 24590073 Free PMC article.
Development of a broad-spectrum antiviral with activity against Ebola virus.
Aman MJ, Kinch MS, Warfield K, Warren T, Yunus A, Enterlein S, Stavale E, Wang P, Chang S, Tang Q, Porter K, Goldblatt M, Bavari S. Aman MJ, et al. Antiviral Res. 2009 Sep;83(3):245-51. doi: 10.1016/j.antiviral.2009.06.001. Epub 2009 Jun 10. Antiviral Res. 2009. PMID: 19523489
Antiviral activity of a small-molecule inhibitor of filovirus infection.
Warren TK, Warfield KL, Wells J, Enterlein S, Smith M, Ruthel G, Yunus AS, Kinch MS, Goldblatt M, Aman MJ, Bavari S. Warren TK, et al. Antimicrob Agents Chemother. 2010 May;54(5):2152-9. doi: 10.1128/AAC.01315-09. Epub 2010 Mar 8. Antimicrob Agents Chemother. 2010. PMID: 20211898 Free PMC article.
Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin.
Radoshitzky SR, Dong L, Chi X, Clester JC, Retterer C, Spurgers K, Kuhn JH, Sandwick S, Ruthel G, Kota K, Boltz D, Warren T, Kranzusch PJ, Whelan SP, Bavari S. Radoshitzky SR, et al. J Virol. 2010 Oct;84(20):10569-80. doi: 10.1128/JVI.00103-10. Epub 2010 Aug 4. J Virol. 2010. PMID: 20686043 Free PMC article.
Alkylated porphyrins have broad antiviral activity against hepadnaviruses, flaviviruses, filoviruses, and arenaviruses.
Guo H, Pan X, Mao R, Zhang X, Wang L, Lu X, Chang J, Guo JT, Passic S, Krebs FC, Wigdahl B, Warren TK, Retterer CJ, Bavari S, Xu X, Cuconati A, Block TM. Guo H, et al. Among authors: warren tk. Antimicrob Agents Chemother. 2011 Feb;55(2):478-86. doi: 10.1128/AAC.00989-10. Epub 2010 Dec 6. Antimicrob Agents Chemother. 2011. PMID: 21135183 Free PMC article.
62 results