Hunt JP - Search Results

1

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology.

Ciceri P, Müller S, O'Mahony A, Fedorov O, Filippakopoulos P, Hunt JP, Lasater EA, Pallares G, Picaud S, Wells C, Martin S, Wodicka LM, Shah NP, Treiber DK, Knapp S. Ciceri P, et al. Among authors: hunt jp. Nat Chem Biol. 2014 Apr;10(4):305-12. doi: 10.1038/nchembio.1471. Epub 2014 Mar 2. Nat Chem Biol. 2014. PMID: 24584101 Free PMC article.

2

Comprehensive analysis of kinase inhibitor selectivity.

Davis MI, Hunt JP, Herrgard S, Ciceri P, Wodicka LM, Pallares G, Hocker M, Treiber DK, Zarrinkar PP. Davis MI, et al. Among authors: hunt jp. Nat Biotechnol. 2011 Oct 30;29(11):1046-51. doi: 10.1038/nbt.1990. Nat Biotechnol. 2011. PMID: 22037378

3

A quantitative analysis of kinase inhibitor selectivity.

Karaman MW, Herrgard S, Treiber DK, Gallant P, Atteridge CE, Campbell BT, Chan KW, Ciceri P, Davis MI, Edeen PT, Faraoni R, Floyd M, Hunt JP, Lockhart DJ, Milanov ZV, Morrison MJ, Pallares G, Patel HK, Pritchard S, Wodicka LM, Zarrinkar PP. Karaman MW, et al. Among authors: hunt jp. Nat Biotechnol. 2008 Jan;26(1):127-32. doi: 10.1038/nbt1358. Nat Biotechnol. 2008. PMID: 18183025

4

Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry.

Wodicka LM, Ciceri P, Davis MI, Hunt JP, Floyd M, Salerno S, Hua XH, Ford JM, Armstrong RC, Zarrinkar PP, Treiber DK. Wodicka LM, et al. Among authors: hunt jp. Chem Biol. 2010 Nov 24;17(11):1241-9. doi: 10.1016/j.chembiol.2010.09.010. Chem Biol. 2010. PMID: 21095574

5

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.

Smith CC, Wang Q, Chin CS, Salerno S, Damon LE, Levis MJ, Perl AE, Travers KJ, Wang S, Hunt JP, Zarrinkar PP, Schadt EE, Kasarskis A, Kuriyan J, Shah NP. Smith CC, et al. Among authors: hunt jp. Nature. 2012 Apr 15;485(7397):260-3. doi: 10.1038/nature11016. Nature. 2012. PMID: 22504184 Free PMC article.

6

Extending kinome coverage by analysis of kinase inhibitor broad profiling data.

Jacoby E, Tresadern G, Bembenek S, Wroblowski B, Buyck C, Neefs JM, Rassokhin D, Poncelet A, Hunt J, van Vlijmen H. Jacoby E, et al. Drug Discov Today. 2015 Jun;20(6):652-8. doi: 10.1016/j.drudis.2015.01.002. Epub 2015 Jan 14. Drug Discov Today. 2015. PMID: 25596550 Review.

7

Transient exposure to quizartinib mediates sustained inhibition of FLT3 signaling while specifically inducing apoptosis in FLT3-activated leukemia cells.

Gunawardane RN, Nepomuceno RR, Rooks AM, Hunt JP, Ricono JM, Belli B, Armstrong RC. Gunawardane RN, et al. Among authors: hunt jp. Mol Cancer Ther. 2013 Apr;12(4):438-47. doi: 10.1158/1535-7163.MCT-12-0305. Epub 2013 Feb 14. Mol Cancer Ther. 2013. PMID: 23412931

8

Traumatic Abdominal Wall Hernia: Management Using a Standardized Approach.

Mejia Morales HG, Lee S, Reed TD, Greiffenstein PP, Schoen JE, Stuke LE, Hunt JP, Marr AB, Harrell KN, Smith AA. Mejia Morales HG, et al. Among authors: hunt jp. Am Surg. 2024 May 27:31348241256060. doi: 10.1177/00031348241256060. Online ahead of print. Am Surg. 2024. PMID: 38803146

9

Global health experience among general surgery residents': Experiences, attitudes, and barriers.

Fitzpatrick-Schmidt T, Leonardi C, Norlin C, Beiter K, Stuke LE, Brown T, Marr A, Greiffenstein P, Schoen J, Hunt JP, Smith A. Fitzpatrick-Schmidt T, et al. Among authors: hunt jp. Am J Surg. 2024 May 3:S0002-9610(24)00268-X. doi: 10.1016/j.amjsurg.2024.05.001. Online ahead of print. Am J Surg. 2024. PMID: 38724292 No abstract available.

10

Risk Factors for Empyema Following Penetrating Diaphragmatic Injuries.

Rewerts LC, Stuke LE, Hunt JP, Marr AB, Schoen JE, Greiffenstein P, Smith AA. Rewerts LC, et al. Among authors: hunt jp. Am Surg. 2024 Apr 20:31348241248700. doi: 10.1177/00031348241248700. Online ahead of print. Am Surg. 2024. PMID: 38642333

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