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Dual kinase-bromodomain inhibitors for rationally designed polypharmacology.
Ciceri P, Müller S, O'Mahony A, Fedorov O, Filippakopoulos P, Hunt JP, Lasater EA, Pallares G, Picaud S, Wells C, Martin S, Wodicka LM, Shah NP, Treiber DK, Knapp S. Ciceri P, et al. Among authors: filippakopoulos p. Nat Chem Biol. 2014 Apr;10(4):305-12. doi: 10.1038/nchembio.1471. Epub 2014 Mar 2. Nat Chem Biol. 2014. PMID: 24584101 Free PMC article.
Structural and functional characterization of the human protein kinase ASK1.
Bunkoczi G, Salah E, Filippakopoulos P, Fedorov O, Müller S, Sobott F, Parker SA, Zhang H, Min W, Turk BE, Knapp S. Bunkoczi G, et al. Among authors: filippakopoulos p. Structure. 2007 Oct;15(10):1215-26. doi: 10.1016/j.str.2007.08.011. Structure. 2007. PMID: 17937911 Free PMC article.
Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3.
Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Atilla-Gokcumen GE, et al. Among authors: filippakopoulos p. Chembiochem. 2008 Dec 15;9(18):2933-6. doi: 10.1002/cbic.200800489. Chembiochem. 2008. PMID: 19035373 Free PMC article. No abstract available.
Structure and functional characterization of the atypical human kinase haspin.
Eswaran J, Patnaik D, Filippakopoulos P, Wang F, Stein RL, Murray JW, Higgins JM, Knapp S. Eswaran J, et al. Among authors: filippakopoulos p. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20198-203. doi: 10.1073/pnas.0901989106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918057 Free PMC article.
SH2 domains: modulators of nonreceptor tyrosine kinase activity.
Filippakopoulos P, Müller S, Knapp S. Filippakopoulos P, et al. Curr Opin Struct Biol. 2009 Dec;19(6):643-9. doi: 10.1016/j.sbi.2009.10.001. Epub 2009 Nov 18. Curr Opin Struct Biol. 2009. PMID: 19926274 Free PMC article. Review.
96 results