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Computer-aided rational molecular design of argifin-derivatives with increased inhibitory activity against chitinase B from Serratia marcescens.
Gouda H, Sunazuka T, Iguchi K, Sugawara A, Hirose T, Noguchi Y, Saito Y, Yanai Y, Yamamoto T, Watanabe T, Shiomi K, Omura S, Hirono S. Gouda H, et al. Among authors: shiomi k. Bioorg Med Chem Lett. 2009 May 15;19(10):2630-3. doi: 10.1016/j.bmcl.2009.04.013. Epub 2009 Apr 9. Bioorg Med Chem Lett. 2009. PMID: 19395258
Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase.
Sugawara A, Maita N, Gouda H, Yamamoto T, Hirose T, Kimura S, Saito Y, Nakano H, Kasai T, Nakano H, Shiomi K, Hirono S, Watanabe T, Taniguchi H, Omura S, Sunazuka T. Sugawara A, et al. Among authors: shiomi k. J Med Chem. 2015 Jun 25;58(12):4984-97. doi: 10.1021/acs.jmedchem.5b00175. Epub 2015 Jun 12. J Med Chem. 2015. PMID: 26030312
610 results