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Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines.
Simoni D, Grisolia G, Giannini G, Roberti M, Rondanin R, Piccagli L, Baruchello R, Rossi M, Romagnoli R, Invidiata FP, Grimaudo S, Jung MK, Hamel E, Gebbia N, Crosta L, Abbadessa V, Di Cristina A, Dusonchet L, Meli M, Tolomeo M. Simoni D, et al. Among authors: meli m. J Med Chem. 2005 Feb 10;48(3):723-36. doi: 10.1021/jm049622b. J Med Chem. 2005. PMID: 15689156
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells.
Rondanin R, Simoni D, Maccesi M, Romagnoli R, Grimaudo S, Pipitone RM, Meli M, Cascio A, Tolomeo M. Rondanin R, et al. Among authors: meli m. ChemMedChem. 2017 Aug 8;12(15):1183-1190. doi: 10.1002/cmdc.201700234. Epub 2017 Jul 19. ChemMedChem. 2017. PMID: 28657677
Programmed cell death (PCD) associated with the stilbene motif of arotinoids: discovery of novel apoptosis inducer agents possessing activity on multidrug resistant tumor cells.
Simoni D, Roberti M, Invidiata FP, Rondanin R, Baruchello R, Malagutti C, Mazzali A, Rossi M, Grimaudo S, Dusonchet L, Meli M, Raimondi MV, D'Alessandro N, Tolomeo M. Simoni D, et al. Among authors: meli m. Bioorg Med Chem Lett. 2000 Dec 4;10(23):2669-73. doi: 10.1016/s0960-894x(00)00547-3. Bioorg Med Chem Lett. 2000. PMID: 11128648
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells.
Simoni D, Roberti M, Invidiata FP, Rondanin R, Baruchello R, Malagutti C, Mazzali A, Rossi M, Grimaudo S, Capone F, Dusonchet L, Meli M, Raimondi MV, Landino M, D'Alessandro N, Tolomeo M, Arindam D, Lu S, Benbrook DM. Simoni D, et al. Among authors: meli m. J Med Chem. 2001 Jul 5;44(14):2308-18. doi: 10.1021/jm0010320. J Med Chem. 2001. PMID: 11428925
From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: synthesis and biological evaluation of valproic esters of 3'-C-methyladenosine.
Petrelli R, Meli M, Vita P, Torquati I, Ferro A, Vodnala M, D'Alessandro N, Tolomeo M, Del Bello F, Kusumanchi P, Franchetti P, Grifantini M, Jayaram HN, Hofer A, Cappellacci L. Petrelli R, et al. Among authors: meli m. Bioorg Med Chem Lett. 2014 Nov 15;24(22):5304-9. doi: 10.1016/j.bmcl.2014.09.046. Epub 2014 Sep 28. Bioorg Med Chem Lett. 2014. PMID: 25304896
441 results