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IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans.
de Luca A, Smeekens SP, Casagrande A, Iannitti R, Conway KL, Gresnigt MS, Begun J, Plantinga TS, Joosten LA, van der Meer JW, Chamilos G, Netea MG, Xavier RJ, Dinarello CA, Romani L, van de Veerdonk FL. de Luca A, et al. Among authors: romani l. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3526-31. doi: 10.1073/pnas.1322831111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550444 Free PMC article.
Antifungal type 1 responses are upregulated in IL-10-deficient mice.
Del Sero G, Mencacci A, Cenci E, d'Ostiani CF, Montagnoli C, Bacci A, Mosci P, Kopf M, Romani L. Del Sero G, et al. Among authors: romani l. Microbes Infect. 1999 Dec;1(14):1169-80. doi: 10.1016/s1286-4579(99)00245-2. Microbes Infect. 1999. PMID: 10580272 Free article.
Provision of antifungal immunity and concomitant alloantigen tolerization by conditioned dendritic cells in experimental hematopoietic transplantation.
Montagnoli C, Perruccio K, Bozza S, Bonifazi P, Zelante T, De Luca A, Moretti S, D'Angelo C, Bistoni F, Martelli M, Aversa F, Velardi A, Romani L. Montagnoli C, et al. Among authors: romani l. Blood Cells Mol Dis. 2008 Jan-Feb;40(1):55-62. doi: 10.1016/j.bcmd.2007.06.016. Epub 2007 Sep 10. Blood Cells Mol Dis. 2008. PMID: 17827038 Review.
IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance.
Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, Belladonna ML, Vacca C, Conte C, Mosci P, Bistoni F, Puccetti P, Kastelein RA, Kopf M, Romani L. Zelante T, et al. Among authors: romani l. Eur J Immunol. 2007 Oct;37(10):2695-706. doi: 10.1002/eji.200737409. Eur J Immunol. 2007. PMID: 17899546 Free article.
Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L. Bozza S, et al. Among authors: romani l. J Immunol. 2008 Mar 15;180(6):4022-31. doi: 10.4049/jimmunol.180.6.4022. J Immunol. 2008. PMID: 18322211
556 results