Macphee I - Search Results

1

Xenobiotic metabolism: the effect of acute kidney injury on non-renal drug clearance and hepatic drug metabolism.

Dixon J, Lane K, Macphee I, Philips B. Dixon J, et al. Among authors: macphee i. Int J Mol Sci. 2014 Feb 13;15(2):2538-53. doi: 10.3390/ijms15022538. Int J Mol Sci. 2014. PMID: 24531139 Free PMC article. Review.

2

Acute kidney injury reduces the hepatic metabolism of midazolam in critically ill patients.

Kirwan CJ, MacPhee IA, Lee T, Holt DW, Philips BJ. Kirwan CJ, et al. Among authors: macphee ia. Intensive Care Med. 2012 Jan;38(1):76-84. doi: 10.1007/s00134-011-2360-8. Epub 2011 Oct 18. Intensive Care Med. 2012. PMID: 22005822

3

The effects of acute renal failure on drug metabolism.

Philips BJ, Lane K, Dixon J, Macphee I. Philips BJ, et al. Among authors: macphee i. Expert Opin Drug Metab Toxicol. 2014 Jan;10(1):11-23. doi: 10.1517/17425255.2013.835802. Epub 2013 Sep 28. Expert Opin Drug Metab Toxicol. 2014. PMID: 24074057 Review.

4

Do statins prevent acute kidney injury?

Philips B, MacPhee I. Philips B, et al. Among authors: macphee i. Expert Opin Drug Saf. 2015 Oct;14(10):1547-61. doi: 10.1517/14740338.2015.1085504. Epub 2015 Sep 12. Expert Opin Drug Saf. 2015. PMID: 26365784 Review.

5

Renohepatic crosstalk: does acute kidney injury cause liver dysfunction?

Lane K, Dixon JJ, MacPhee IA, Philips BJ. Lane K, et al. Nephrol Dial Transplant. 2013 Jul;28(7):1634-47. doi: 10.1093/ndt/gft091. Epub 2013 May 17. Nephrol Dial Transplant. 2013. PMID: 23685679 Review.

6

Using midazolam to monitor changes in hepatic drug metabolism in critically ill patients.

Kirwan CJ, Lee T, Holt DW, Grounds RM, MacPhee IA, Philips BJ. Kirwan CJ, et al. Intensive Care Med. 2009 Jul;35(7):1271-5. doi: 10.1007/s00134-009-1430-7. Epub 2009 Feb 7. Intensive Care Med. 2009. PMID: 19198803 Clinical Trial.

7

Using drug probes to monitor hepatic drug metabolism in critically ill patients: midazolam, a flawed but useful tool for clinical investigation of CYP3A activity?

Kirwan C, MacPhee I, Philips B. Kirwan C, et al. Among authors: macphee i. Expert Opin Drug Metab Toxicol. 2010 Jun;6(6):761-71. doi: 10.1517/17425255.2010.482929. Expert Opin Drug Metab Toxicol. 2010. PMID: 20402562 Review.

8

Using tramadol to measure CYP2D6 metabolism in critically ill adults.

Lane K, Dixon JJ, McKeown D, Johnston A, van Schaik RH, van Fessem M, MacPhee IA, Philips BJ. Lane K, et al. Intensive Care Med. 2014 Aug;40(8):1177-8. doi: 10.1007/s00134-014-3372-y. Epub 2014 Jun 27. Intensive Care Med. 2014. PMID: 24968714 No abstract available.

9

Validation of a continuous infusion of low dose Iohexol to measure glomerular filtration rate: randomised clinical trial.

Dixon JJ, Lane K, Dalton RN, Turner C, Grounds RM, MacPhee IA, Philips BJ. Dixon JJ, et al. J Transl Med. 2015 Feb 12;13:58. doi: 10.1186/s12967-015-0414-3. J Transl Med. 2015. PMID: 25885409 Free PMC article. Clinical Trial.

10

Continuous Infusion of Low-Dose Iohexol Measures Changing Glomerular Filtration Rate in Critically Ill Patients.

Dixon JJ, Lane K, Dalton RN, Turner C, MacPhee IAM, Chis Ster I, Philips BJ. Dixon JJ, et al. Among authors: macphee iam. Crit Care Med. 2018 Mar;46(3):e190-e197. doi: 10.1097/CCM.0000000000002870. Crit Care Med. 2018. PMID: 29194145

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