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Viral enhancer mimicry of host innate-immune promoters.
Kropp KA, Angulo A, Ghazal P. Kropp KA, et al. Among authors: ghazal p. PLoS Pathog. 2014 Feb 6;10(2):e1003804. doi: 10.1371/journal.ppat.1003804. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24516378 Free PMC article. Review. No abstract available.
Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection.
Rodríguez-Martín S, Kropp KA, Wilhelmi V, Lisnic VJ, Hsieh WY, Blanc M, Livingston A, Busche A, Tekotte H, Messerle M, Auer M, Fraser I, Jonjic S, Angulo A, Reddehase MJ, Ghazal P. Rodríguez-Martín S, et al. Among authors: ghazal p. PLoS Pathog. 2012;8(8):e1002901. doi: 10.1371/journal.ppat.1002901. Epub 2012 Aug 30. PLoS Pathog. 2012. PMID: 22952450 Free PMC article.
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.
Blanc M, Hsieh WY, Robertson KA, Watterson S, Shui G, Lacaze P, Khondoker M, Dickinson P, Sing G, Rodríguez-Martín S, Phelan P, Forster T, Strobl B, Müller M, Riemersma R, Osborne T, Wenk MR, Angulo A, Ghazal P. Blanc M, et al. Among authors: ghazal p. PLoS Biol. 2011 Mar;9(3):e1000598. doi: 10.1371/journal.pbio.1000598. Epub 2011 Mar 8. PLoS Biol. 2011. PMID: 21408089 Free PMC article.
Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state.
Kropp KA, Robertson KA, Sing G, Rodriguez-Martin S, Blanc M, Lacaze P, Hassim MF, Khondoker MR, Busche A, Dickinson P, Forster T, Strobl B, Mueller M, Jonjic S, Angulo A, Ghazal P. Kropp KA, et al. Among authors: ghazal p. J Virol. 2011 Oct;85(19):10286-99. doi: 10.1128/JVI.00373-11. Epub 2011 Jul 20. J Virol. 2011. PMID: 21775459 Free PMC article.
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.
Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P. Blanc M, et al. Among authors: ghazal p. Immunity. 2013 Jan 24;38(1):106-18. doi: 10.1016/j.immuni.2012.11.004. Epub 2012 Dec 27. Immunity. 2013. PMID: 23273843 Free PMC article.
257 results