Xie L - Search Results

1

Optimization of 4-(N-cycloamino)phenylquinazolines as a novel class of tubulin-polymerization inhibitors targeting the colchicine site.

Wang XF, Guan F, Ohkoshi E, Guo W, Wang L, Zhu DQ, Wang SB, Wang LT, Hamel E, Yang D, Li L, Qian K, Morris-Natschke SL, Yuan S, Lee KH, Xie L. Wang XF, et al. Among authors: xie l. J Med Chem. 2014 Feb 27;57(4):1390-402. doi: 10.1021/jm4016526. Epub 2014 Feb 6. J Med Chem. 2014. PMID: 24502232 Free PMC article.

2

Recent progress in the development of coumarin derivatives as potent anti-HIV agents.

Yu D, Suzuki M, Xie L, Morris-Natschke SL, Lee KH. Yu D, et al. Among authors: xie l. Med Res Rev. 2003 May;23(3):322-45. doi: 10.1002/med.10034. Med Res Rev. 2003. PMID: 12647313 Review.

3

Anti-AIDS agents. 52. Synthesis and anti-HIV activity of hydroxymethyl (3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone derivatives.

Xie L, Yu D, Wild C, Allaway G, Turpin J, Smith PC, Lee KH. Xie L, et al. J Med Chem. 2004 Jan 29;47(3):756-60. doi: 10.1021/jm030416y. J Med Chem. 2004. PMID: 14736256

4

Molecular modeling, design, synthesis, and biological evaluation of novel 3',4'-dicamphanoyl-(+)-cis-khellactone (DCK) analogs as potent anti-HIV agents.

Xie L, Zhao CH, Zhou T, Chen HF, Fan BT, Chen XH, Ma JZ, Li JY, Bao ZY, Lo Z, Yu D, Lee KH. Xie L, et al. Bioorg Med Chem. 2005 Dec 1;13(23):6435-49. doi: 10.1016/j.bmc.2005.06.057. Epub 2005 Aug 2. Bioorg Med Chem. 2005. PMID: 16061386

5

Synthesis of unsymmetrical biphenyls as potent cytotoxic agents.

Wu G, Guo HF, Gao K, Liu YN, Bastow KF, Morris-Natschke SL, Lee KH, Xie L. Wu G, et al. Among authors: xie l. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5272-6. doi: 10.1016/j.bmcl.2008.08.050. Epub 2008 Aug 22. Bioorg Med Chem Lett. 2008. PMID: 18782668 Free PMC article.

6

Development and preclinical studies of broad-spectrum anti-HIV agent (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-cyanomethyl-4-methyl-DCK).

Xie L, Guo HF, Lu H, Zhuang XM, Zhang AM, Wu G, Ruan JX, Zhou T, Yu D, Qian K, Lee KH, Jiang S. Xie L, et al. J Med Chem. 2008 Dec 25;51(24):7689-96. doi: 10.1021/jm8003009. J Med Chem. 2008. PMID: 19053755 Free PMC article.

7

Design, synthesis, and biological evaluation of N-carboxyphenylpyrrole derivatives as potent HIV fusion inhibitors targeting gp41.

Liu K, Lu H, Hou L, Qi Z, Teixeira C, Barbault F, Fan BT, Liu S, Jiang S, Xie L. Liu K, et al. Among authors: xie l. J Med Chem. 2008 Dec 25;51(24):7843-54. doi: 10.1021/jm800869t. J Med Chem. 2008. PMID: 19053778 Free PMC article.

8

Discovery of diarylpyridine derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Tian X, Qin B, Lu H, Lai W, Jiang S, Lee KH, Chen CH, Xie L. Tian X, et al. Among authors: xie l. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5482-5. doi: 10.1016/j.bmcl.2009.07.080. Epub 2009 Jul 19. Bioorg Med Chem Lett. 2009. PMID: 19666220 Free PMC article.

9

Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors.

Qin B, Jiang X, Lu H, Tian X, Barbault F, Huang L, Qian K, Chen CH, Huang R, Jiang S, Lee KH, Xie L. Qin B, et al. Among authors: xie l. J Med Chem. 2010 Jul 8;53(13):4906-16. doi: 10.1021/jm1002952. J Med Chem. 2010. PMID: 20527972 Free PMC article.

10

Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Tian X, Qin B, Wu Z, Wang X, Lu H, Morris-Natschke SL, Chen CH, Jiang S, Lee KH, Xie L. Tian X, et al. Among authors: xie l. J Med Chem. 2010 Dec 9;53(23):8287-97. doi: 10.1021/jm100738d. Epub 2010 Nov 4. J Med Chem. 2010. PMID: 21049929 Free PMC article.

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