Rathmell JC - Search Results

1

Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype.

Freemerman AJ, Johnson AR, Sacks GN, Milner JJ, Kirk EL, Troester MA, Macintyre AN, Goraksha-Hicks P, Rathmell JC, Makowski L. Freemerman AJ, et al. Among authors: rathmell jc. J Biol Chem. 2014 Mar 14;289(11):7884-96. doi: 10.1074/jbc.M113.522037. Epub 2014 Feb 3. J Biol Chem. 2014. PMID: 24492615 Free PMC article.

2

Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation.

Zhao Y, Coloff JL, Ferguson EC, Jacobs SR, Cui K, Rathmell JC. Zhao Y, et al. Among authors: rathmell jc. J Biol Chem. 2008 Dec 26;283(52):36344-53. doi: 10.1074/jbc.M803580200. Epub 2008 Nov 6. J Biol Chem. 2008. PMID: 18990690 Free PMC article.

3

TGF-beta: a new role for an old AktTOR.

Goraksha-Hicks P, Rathmell JC. Goraksha-Hicks P, et al. Among authors: rathmell jc. Dev Cell. 2009 Jul;17(1):6-8. doi: 10.1016/j.devcel.2009.07.004. Dev Cell. 2009. PMID: 19619487 Free PMC article.

4

Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl.

Mason EF, Zhao Y, Goraksha-Hicks P, Coloff JL, Gannon H, Jones SN, Rathmell JC. Mason EF, et al. Among authors: rathmell jc. Cancer Res. 2010 Oct 15;70(20):8066-76. doi: 10.1158/0008-5472.CAN-10-0608. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876800 Free PMC article.

5

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

Michalek RD, Gerriets VA, Jacobs SR, Macintyre AN, MacIver NJ, Mason EF, Sullivan SA, Nichols AG, Rathmell JC. Michalek RD, et al. Among authors: rathmell jc. J Immunol. 2011 Mar 15;186(6):3299-303. doi: 10.4049/jimmunol.1003613. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317389 Free PMC article.

6

Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.

Coloff JL, Macintyre AN, Nichols AG, Liu T, Gallo CA, Plas DR, Rathmell JC. Coloff JL, et al. Among authors: rathmell jc. Cancer Res. 2011 Aug 1;71(15):5204-13. doi: 10.1158/0008-5472.CAN-10-4531. Epub 2011 Jun 13. Cancer Res. 2011. PMID: 21670080 Free PMC article.

7

PKM2 and the tricky balance of growth and energy in cancer.

Macintyre AN, Rathmell JC. Macintyre AN, et al. Among authors: rathmell jc. Mol Cell. 2011 Jun 24;42(6):713-4. doi: 10.1016/j.molcel.2011.06.003. Mol Cell. 2011. PMID: 21700216 Free PMC article.

8

Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma.

Bhatt AP, Jacobs SR, Freemerman AJ, Makowski L, Rathmell JC, Dittmer DP, Damania B. Bhatt AP, et al. Among authors: rathmell jc. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11818-23. doi: 10.1073/pnas.1205995109. Epub 2012 Jun 29. Proc Natl Acad Sci U S A. 2012. PMID: 22752304 Free PMC article.

9

Activated lymphocytes as a metabolic model for carcinogenesis.

Macintyre AN, Rathmell JC. Macintyre AN, et al. Among authors: rathmell jc. Cancer Metab. 2013 Jan 23;1(1):5. doi: 10.1186/2049-3002-1-5. Cancer Metab. 2013. PMID: 24280044 Free PMC article.

10

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.

Macintyre AN, Gerriets VA, Nichols AG, Michalek RD, Rudolph MC, Deoliveira D, Anderson SM, Abel ED, Chen BJ, Hale LP, Rathmell JC. Macintyre AN, et al. Among authors: rathmell jc. Cell Metab. 2014 Jul 1;20(1):61-72. doi: 10.1016/j.cmet.2014.05.004. Epub 2014 Jun 12. Cell Metab. 2014. PMID: 24930970 Free PMC article.

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