Macintyre AN - Search Results

1

Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype.

Freemerman AJ, Johnson AR, Sacks GN, Milner JJ, Kirk EL, Troester MA, Macintyre AN, Goraksha-Hicks P, Rathmell JC, Makowski L. Freemerman AJ, et al. Among authors: macintyre an. J Biol Chem. 2014 Mar 14;289(11):7884-96. doi: 10.1074/jbc.M113.522037. Epub 2014 Feb 3. J Biol Chem. 2014. PMID: 24492615 Free PMC article.

2

Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis.

Liu T, Kishton RJ, Macintyre AN, Gerriets VA, Xiang H, Liu X, Abel ED, Rizzieri D, Locasale JW, Rathmell JC. Liu T, et al. Among authors: macintyre an. Cell Death Dis. 2014 Oct 16;5(10):e1470. doi: 10.1038/cddis.2014.431. Cell Death Dis. 2014. PMID: 25321477 Free PMC article.

3

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.

Macintyre AN, Gerriets VA, Nichols AG, Michalek RD, Rudolph MC, Deoliveira D, Anderson SM, Abel ED, Chen BJ, Hale LP, Rathmell JC. Macintyre AN, et al. Cell Metab. 2014 Jul 1;20(1):61-72. doi: 10.1016/j.cmet.2014.05.004. Epub 2014 Jun 12. Cell Metab. 2014. PMID: 24930970 Free PMC article.

4

AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.

Kishton RJ, Barnes CE, Nichols AG, Cohen S, Gerriets VA, Siska PJ, Macintyre AN, Goraksha-Hicks P, de Cubas AA, Liu T, Warmoes MO, Abel ED, Yeoh AE, Gershon TR, Rathmell WK, Richards KL, Locasale JW, Rathmell JC. Kishton RJ, et al. Among authors: macintyre an. Cell Metab. 2016 Apr 12;23(4):649-62. doi: 10.1016/j.cmet.2016.03.008. Cell Metab. 2016. PMID: 27076078 Free PMC article.

5

Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis.

Altman BJ, Jacobs SR, Mason EF, Michalek RD, MacIntyre AN, Coloff JL, Ilkayeva O, Jia W, He YW, Rathmell JC. Altman BJ, et al. Among authors: macintyre an. Oncogene. 2011 Apr 21;30(16):1855-67. doi: 10.1038/onc.2010.561. Epub 2010 Dec 13. Oncogene. 2011. PMID: 21151168 Free PMC article.

6

Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells.

Cao Y, Rathmell JC, Macintyre AN. Cao Y, et al. Among authors: macintyre an. PLoS One. 2014 Aug 4;9(8):e104104. doi: 10.1371/journal.pone.0104104. eCollection 2014. PLoS One. 2014. PMID: 25090630 Free PMC article.

7

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

Michalek RD, Gerriets VA, Jacobs SR, Macintyre AN, MacIver NJ, Mason EF, Sullivan SA, Nichols AG, Rathmell JC. Michalek RD, et al. Among authors: macintyre an. J Immunol. 2011 Mar 15;186(6):3299-303. doi: 10.4049/jimmunol.1003613. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317389 Free PMC article.

8

Activated lymphocytes as a metabolic model for carcinogenesis.

Macintyre AN, Rathmell JC. Macintyre AN, et al. Cancer Metab. 2013 Jan 23;1(1):5. doi: 10.1186/2049-3002-1-5. Cancer Metab. 2013. PMID: 24280044 Free PMC article.

9

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

Ho PC, Bihuniak JD, Macintyre AN, Staron M, Liu X, Amezquita R, Tsui YC, Cui G, Micevic G, Perales JC, Kleinstein SH, Abel ED, Insogna KL, Feske S, Locasale JW, Bosenberg MW, Rathmell JC, Kaech SM. Ho PC, et al. Among authors: macintyre an. Cell. 2015 Sep 10;162(6):1217-28. doi: 10.1016/j.cell.2015.08.012. Epub 2015 Aug 27. Cell. 2015. PMID: 26321681 Free PMC article.

10

Targeting Glycolysis in Alloreactive T Cells to Prevent Acute Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia Effect.

Huang Y, Zou Y, Jiao Y, Shi P, Nie X, Huang W, Xiong C, Choi M, Huang C, Macintyre AN, Nichols A, Li F, Li CY, MacIver NJ, Cardona DM, Brennan TV, Li Z, Chao NJ, Rathmell JC, Chen BJ. Huang Y, et al. Among authors: macintyre an. Front Immunol. 2022 Feb 28;13:751296. doi: 10.3389/fimmu.2022.751296. eCollection 2022. Front Immunol. 2022. PMID: 35296079 Free PMC article.

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