Bamezai RN - Search Results

1

Missense mutations in pyruvate kinase M2 promote cancer metabolism, oxidative endurance, anchorage independence, and tumor growth in a dominant negative manner.

Iqbal MA, Siddiqui FA, Chaman N, Gupta V, Kumar B, Gopinath P, Bamezai RN. Iqbal MA, et al. Among authors: bamezai rn. J Biol Chem. 2014 Mar 21;289(12):8098-105. doi: 10.1074/jbc.M113.515742. Epub 2014 Feb 3. J Biol Chem. 2014. PMID: 24492614 Free PMC article.

2

Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.

Iqbal MA, Siddiqui FA, Gupta V, Chattopadhyay S, Gopinath P, Kumar B, Manvati S, Chaman N, Bamezai RN. Iqbal MA, et al. Among authors: bamezai rn. Mol Cancer. 2013 Jul 9;12:72. doi: 10.1186/1476-4598-12-72. Mol Cancer. 2013. PMID: 23837608 Free PMC article.

3

Pyruvate kinase M2 and cancer: an updated assessment.

Iqbal MA, Gupta V, Gopinath P, Mazurek S, Bamezai RN. Iqbal MA, et al. Among authors: bamezai rn. FEBS Lett. 2014 Aug 19;588(16):2685-92. doi: 10.1016/j.febslet.2014.04.011. Epub 2014 Apr 18. FEBS Lett. 2014. PMID: 24747424 Free article. Review.

4

ERK2-Pyruvate Kinase Axis Permits Phorbol 12-Myristate 13-Acetate-induced Megakaryocyte Differentiation in K562 Cells.

Chaman N, Iqbal MA, Siddiqui FA, Gopinath P, Bamezai RN. Chaman N, et al. Among authors: bamezai rn. J Biol Chem. 2015 Sep 25;290(39):23803-15. doi: 10.1074/jbc.M115.657411. Epub 2015 Aug 12. J Biol Chem. 2015. PMID: 26269597 Free PMC article.

5

Differential behavior of missense mutations in the intersubunit contact domain of the human pyruvate kinase M2 isozyme.

Akhtar K, Gupta V, Koul A, Alam N, Bhat R, Bamezai RN. Akhtar K, et al. Among authors: bamezai rn. J Biol Chem. 2009 May 1;284(18):11971-81. doi: 10.1074/jbc.M808761200. Epub 2009 Mar 5. J Biol Chem. 2009. PMID: 19265196 Free PMC article.

6

Dominant negative mutations affect oligomerization of human pyruvate kinase M2 isozyme and promote cellular growth and polyploidy.

Gupta V, Kalaiarasan P, Faheem M, Singh N, Iqbal MA, Bamezai RN. Gupta V, et al. Among authors: bamezai rn. J Biol Chem. 2010 May 28;285(22):16864-73. doi: 10.1074/jbc.M109.065029. Epub 2010 Mar 19. J Biol Chem. 2010. PMID: 20304929 Free PMC article.

7

Human pyruvate kinase M2: a multifunctional protein.

Gupta V, Bamezai RN. Gupta V, et al. Among authors: bamezai rn. Protein Sci. 2010 Nov;19(11):2031-44. doi: 10.1002/pro.505. Protein Sci. 2010. PMID: 20857498 Free PMC article. Review.

8

Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin.

Iqbal MA, Bamezai RN. Iqbal MA, et al. Among authors: bamezai rn. PLoS One. 2012;7(5):e36764. doi: 10.1371/journal.pone.0036764. Epub 2012 May 4. PLoS One. 2012. PMID: 22574221 Free PMC article.

9

Pyruvate kinase M2: regulatory circuits and potential for therapeutic intervention.

Gupta V, Wellen KE, Mazurek S, Bamezai RN. Gupta V, et al. Among authors: bamezai rn. Curr Pharm Des. 2014;20(15):2595-606. doi: 10.2174/13816128113199990484. Curr Pharm Des. 2014. PMID: 23859618 Review.

10

Interplay between epigenetics & cancer metabolism.

Gupta V, Gopinath P, Iqbal MA, Mazurek S, Wellen KE, Bamezai RN. Gupta V, et al. Among authors: bamezai rn. Curr Pharm Des. 2014;20(11):1706-14. doi: 10.2174/13816128113199990536. Curr Pharm Des. 2014. PMID: 23888952

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