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Protein kinase CK2-dependent phosphorylation of the human Regulators of Calcineurin reveals a novel mechanism regulating the calcineurin-NFATc signaling pathway.
Martínez-Høyer S, Aranguren-Ibáñez A, García-García J, Serrano-Candelas E, Vilardell J, Nunes V, Aguado F, Oliva B, Itarte E, Pérez-Riba M. Martínez-Høyer S, et al. Biochim Biophys Acta. 2013 Oct;1833(10):2311-21. doi: 10.1016/j.bbamcr.2013.05.021. Epub 2013 Jun 1. Biochim Biophys Acta. 2013. PMID: 23732701 Free article.
RCAN 1 and 3 proteins regulate thymic positive selection.
Serrano-Candelas E, Alemán-Muench G, Solé-Sánchez S, Aubareda A, Martínez-Høyer S, Adán J, Aranguren-Ibáñez Á, Pritchard MA, Soldevila G, Pérez-Riba M. Serrano-Candelas E, et al. Among authors: martinez hoyer s. Biochem Biophys Res Commun. 2015 May 1;460(2):295-301. doi: 10.1016/j.bbrc.2015.03.029. Epub 2015 Mar 14. Biochem Biophys Res Commun. 2015. PMID: 25783055
Inhibiting the calcineurin-NFAT (nuclear factor of activated T cells) signaling pathway with a regulator of calcineurin-derived peptide without affecting general calcineurin phosphatase activity.
Mulero MC, Aubareda A, Orzáez M, Messeguer J, Serrano-Candelas E, Martínez-Hoyer S, Messeguer A, Pérez-Payá E, Pérez-Riba M. Mulero MC, et al. J Biol Chem. 2009 Apr 3;284(14):9394-401. doi: 10.1074/jbc.M805889200. Epub 2009 Feb 3. J Biol Chem. 2009. PMID: 19189965 Free PMC article.
A novel role for an RCAN3-derived peptide as a tumor suppressor in breast cancer.
Martínez-Høyer S, Solé-Sánchez S, Aguado F, Martínez-Martínez S, Serrano-Candelas E, Hernández JL, Iglesias M, Redondo JM, Casanovas O, Messeguer R, Pérez-Riba M. Martínez-Høyer S, et al. Carcinogenesis. 2015 Jul;36(7):792-9. doi: 10.1093/carcin/bgv056. Epub 2015 Apr 26. Carcinogenesis. 2015. PMID: 25916653
Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization.
Guasch A, Aranguren-Ibáñez Á, Pérez-Luque R, Aparicio D, Martínez-Høyer S, Mulero MC, Serrano-Candelas E, Pérez-Riba M, Fita I. Guasch A, et al. Among authors: martinez hoyer s. PLoS One. 2015 Aug 6;10(8):e0134569. doi: 10.1371/journal.pone.0134569. eCollection 2015. PLoS One. 2015. PMID: 26248042 Free PMC article.
Mechanisms of lenalidomide sensitivity and resistance.
Martinez-Høyer S, Karsan A. Martinez-Høyer S, et al. Exp Hematol. 2020 Nov;91:22-31. doi: 10.1016/j.exphem.2020.09.196. Epub 2020 Oct 9. Exp Hematol. 2020. PMID: 32976949 Free article. Review.
Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome.
Martinez-Høyer S, Deng Y, Parker J, Jiang J, Mo A, Docking TR, Gharaee N, Li J, Umlandt P, Fuller M, Jädersten M, Kulasekararaj A, Malcovati L, List AF, Hellström-Lindberg E, Platzbecker U, Karsan A. Martinez-Høyer S, et al. Nat Cell Biol. 2020 May;22(5):526-533. doi: 10.1038/s41556-020-0497-9. Epub 2020 Apr 6. Nat Cell Biol. 2020. PMID: 32251398
A clinical transcriptome approach to patient stratification and therapy selection in acute myeloid leukemia.
Docking TR, Parker JDK, Jädersten M, Duns G, Chang L, Jiang J, Pilsworth JA, Swanson LA, Chan SK, Chiu R, Nip KM, Mar S, Mo A, Wang X, Martinez-Høyer S, Stubbins RJ, Mungall KL, Mungall AJ, Moore RA, Jones SJM, Birol İ, Marra MA, Hogge D, Karsan A. Docking TR, et al. Among authors: martinez hoyer s. Nat Commun. 2021 Apr 30;12(1):2474. doi: 10.1038/s41467-021-22625-y. Nat Commun. 2021. PMID: 33931648 Free PMC article.
12 results