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Molecular tweezers targeting transthyretin amyloidosis.
Ferreira N, Pereira-Henriques A, Attar A, Klärner FG, Schrader T, Bitan G, Gales L, Saraiva MJ, Almeida MR. Ferreira N, et al. Among authors: almeida mr. Neurotherapeutics. 2014 Apr;11(2):450-61. doi: 10.1007/s13311-013-0256-8. Neurotherapeutics. 2014. PMID: 24459092 Free PMC article.
Iodination of salicylic acid improves its binding to transthyretin.
Gales L, Almeida MR, Arsequell G, Valencia G, Saraiva MJ, Damas AM. Gales L, et al. Among authors: almeida mr. Biochim Biophys Acta. 2008 Mar;1784(3):512-7. doi: 10.1016/j.bbapap.2007.11.014. Epub 2007 Dec 3. Biochim Biophys Acta. 2008. PMID: 18155178
Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors.
González A, Quirante J, Nieto J, Almeida MR, Saraiva MJ, Planas A, Arsequell G, Valencia G. González A, et al. Among authors: almeida mr. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5270-3. doi: 10.1016/j.bmcl.2009.03.004. Epub 2009 Mar 6. Bioorg Med Chem Lett. 2009. PMID: 19651509
377 results