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Selenium induces a multi-targeted cell death process in addition to ROS formation.
J Cell Mol Med. 2014 Apr;18(4):671-84. doi: 10.1111/jcmm.12214. Epub 2014 Jan 8.
J Cell Mol Med. 2014.
PMID: 24400844
Free PMC article.
Selenium compounds are substrates for glutaredoxins: a novel pathway for selenium metabolism and a potential mechanism for selenium-mediated cytotoxicity.
Wallenberg M, Olm E, Hebert C, Björnstedt M, Fernandes AP.
Wallenberg M, et al.
Biochem J. 2010 Jul 1;429(1):85-93. doi: 10.1042/BJ20100368.
Biochem J. 2010.
PMID: 20408818
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Methylselenol formed by spontaneous methylation of selenide is a superior selenium substrate to the thioredoxin and glutaredoxin systems.
Fernandes AP, Wallenberg M, Gandin V, Misra S, Tisato F, Marzano C, Rigobello MP, Kumar S, Björnstedt M.
Fernandes AP, et al. Among authors: wallenberg m.
PLoS One. 2012;7(11):e50727. doi: 10.1371/journal.pone.0050727. Epub 2012 Nov 30.
PLoS One. 2012.
PMID: 23226364
Free PMC article.
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Selenium cytotoxicity in cancer.
Wallenberg M, Misra S, Björnstedt M.
Wallenberg M, et al.
Basic Clin Pharmacol Toxicol. 2014 May;114(5):377-86. doi: 10.1111/bcpt.12207. Epub 2014 Mar 3.
Basic Clin Pharmacol Toxicol. 2014.
PMID: 24529300
Free article.
Review.
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Selenite promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells.
Misra S, Selvam AK, Wallenberg M, Ambati A, Matolcsy A, Magalhaes I, Lauter G, Björnstedt M.
Misra S, et al. Among authors: wallenberg m.
Oncotarget. 2016 Nov 15;7(46):74686-74700. doi: 10.18632/oncotarget.12531.
Oncotarget. 2016.
PMID: 27732960
Free PMC article.
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Pharmacokinetics and Toxicity of Sodium Selenite in the Treatment of Patients with Carcinoma in a Phase I Clinical Trial: The SECAR Study.
Brodin O, Eksborg S, Wallenberg M, Asker-Hagelberg C, Larsen EH, Mohlkert D, Lenneby-Helleday C, Jacobsson H, Linder S, Misra S, Björnstedt M.
Brodin O, et al. Among authors: wallenberg m.
Nutrients. 2015 Jun 19;7(6):4978-94. doi: 10.3390/nu7064978.
Nutrients. 2015.
PMID: 26102212
Free PMC article.
Clinical Trial.
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Genome-wide association study of liver enzyme elevation in an extended cohort of rheumatoid arthritis patients starting low-dose methotrexate.
Cavalli M, Eriksson N, Sundbaum JK, Wallenberg M, Kohnke H, Baecklund E, Hallberg P, Wadelius M.
Cavalli M, et al. Among authors: wallenberg m.
Pharmacogenomics. 2022 Oct;23(15):813-820. doi: 10.2217/pgs-2022-0074. Epub 2022 Sep 7.
Pharmacogenomics. 2022.
PMID: 36070248
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Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate.
Sundbaum JK, Baecklund E, Eriksson N, Kohnke H, Wallenberg M, Cavalli M, Wadelius C, Wadelius M, Hallberg P.
Sundbaum JK, et al. Among authors: wallenberg m.
Pharmacogenomics. 2021 Oct;22(15):973-982. doi: 10.2217/pgs-2021-0064. Epub 2021 Sep 15.
Pharmacogenomics. 2021.
PMID: 34521259
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