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Evolving therapies and FAK inhibitors for the treatment of cancer.
Dunn KB, Heffler M, Golubovskaya VM. Dunn KB, et al. Among authors: golubovskaya vm. Anticancer Agents Med Chem. 2010 Dec;10(10):722-34. doi: 10.2174/187152010794728657. Anticancer Agents Med Chem. 2010. PMID: 21291406 Free PMC article. Review.
FAK and p53 protein interactions.
Golubovskaya VM, Cance WG. Golubovskaya VM, et al. Anticancer Agents Med Chem. 2011 Sep;11(7):617-9. doi: 10.2174/187152011796817619. Anticancer Agents Med Chem. 2011. PMID: 21355845 Free PMC article. Review.
FAK and Nanog cross talk with p53 in cancer stem cells.
Golubovskaya VM. Golubovskaya VM. Anticancer Agents Med Chem. 2013 May;13(4):576-80. doi: 10.2174/1871520611313040006. Anticancer Agents Med Chem. 2013. PMID: 22934707 Free PMC article. Review.
A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo.
Golubovskaya VM, Figel S, Ho BT, Johnson CP, Yemma M, Huang G, Zheng M, Nyberg C, Magis A, Ostrov DA, Gelman IH, Cance WG. Golubovskaya VM, et al. Carcinogenesis. 2012 May;33(5):1004-13. doi: 10.1093/carcin/bgs120. Epub 2012 Mar 7. Carcinogenesis. 2012. PMID: 22402131 Free PMC article.
88 results