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Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays.
Semenova MN, Kiselyov AS, Tsyganov DV, Konyushkin LD, Firgang SI, Semenov RV, Malyshev OR, Raihstat MM, Fuchs F, Stielow A, Lantow M, Philchenkov AA, Zavelevich MP, Zefirov NS, Kuznetsov SA, Semenov VV. Semenova MN, et al. Among authors: konyushkin ld. J Med Chem. 2011 Oct 27;54(20):7138-49. doi: 10.1021/jm200737s. Epub 2011 Sep 29. J Med Chem. 2011. PMID: 21916509
Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines.
Demchuk DV, Samet AV, Chernysheva NB, Ushkarov VI, Stashina GA, Konyushkin LD, Raihstat MM, Firgang SI, Philchenkov AA, Zavelevich MP, Kuiava LM, Chekhun VF, Blokhin DY, Kiselyov AS, Semenova MN, Semenov VV. Demchuk DV, et al. Among authors: konyushkin ld. Bioorg Med Chem. 2014 Jan 15;22(2):738-55. doi: 10.1016/j.bmc.2013.12.015. Epub 2013 Dec 12. Bioorg Med Chem. 2014. PMID: 24387982
A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
Stepanov AI, Astrat'ev AA, Sheremetev AB, Lagutina NK, Palysaeva NV, Tyurin AY, Aleksandrova NS, Sadchikova NP, Suponitsky KY, Atamanenko OP, Konyushkin LD, Semenov RV, Firgang SI, Kiselyov AS, Semenova MN, Semenov VV. Stepanov AI, et al. Among authors: konyushkin ld. Eur J Med Chem. 2015 Apr 13;94:237-51. doi: 10.1016/j.ejmech.2015.02.051. Epub 2015 Feb 28. Eur J Med Chem. 2015. PMID: 25768706
Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity.
Semenov VV, Tsyganov DV, Semenova MN, Chuprov-Netochin RN, Raihstat MM, Konyushkin LD, Volynchuk PB, Marusich EI, Nazarenko VV, Leonov SV, Kiselyov AS. Semenov VV, et al. Among authors: konyushkin ld. J Nat Prod. 2016 May 27;79(5):1429-38. doi: 10.1021/acs.jnatprod.6b00173. Epub 2016 Apr 21. J Nat Prod. 2016. PMID: 27100701
Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones: In vivo and cell-based studies.
Semenov VV, Lichitsky BV, Komogortsev AN, Dudinov AA, Krayushkin MM, Konyushkin LD, Atamanenko OP, Karmanova IB, Strelenko YA, Shor B, Semenova MN, Kiselyov AS. Semenov VV, et al. Among authors: konyushkin ld. Eur J Med Chem. 2017 Jan 5;125:573-585. doi: 10.1016/j.ejmech.2016.09.075. Epub 2016 Sep 24. Eur J Med Chem. 2017. PMID: 27718473
Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents.
Semenova MN, Demchuk DV, Tsyganov DV, Chernysheva NB, Samet AV, Silyanova EA, Kislyi VP, Maksimenko AS, Varakutin AE, Konyushkin LD, Raihstat MM, Kiselyov AS, Semenov VV. Semenova MN, et al. Among authors: konyushkin ld. ACS Comb Sci. 2018 Dec 10;20(12):700-721. doi: 10.1021/acscombsci.8b00113. Epub 2018 Nov 29. ACS Comb Sci. 2018. PMID: 30452225
15 results