Ding T - Search Results

1

Identification of small molecule sphingomyelin synthase inhibitors.

Deng X, Lin F, Zhang Y, Li Y, Zhou L, Lou B, Li Y, Dong J, Ding T, Jiang X, Wang R, Ye D. Deng X, et al. Among authors: ding t. Eur J Med Chem. 2014 Feb 12;73:1-7. doi: 10.1016/j.ejmech.2013.12.002. Epub 2013 Dec 14. Eur J Med Chem. 2014. PMID: 24374347

2

Sphingomyelin synthase overexpression increases cholesterol accumulation and decreases cholesterol secretion in liver cells.

Yan N, Ding T, Dong J, Li Y, Wu M. Yan N, et al. Among authors: ding t. Lipids Health Dis. 2011 Mar 21;10:46. doi: 10.1186/1476-511X-10-46. Lipids Health Dis. 2011. PMID: 21418611 Free PMC article.

3

Subcellular targeting domains of sphingomyelin synthase 1 and 2.

Yeang C, Ding T, Chirico WJ, Jiang XC. Yeang C, et al. Among authors: ding t. Nutr Metab (Lond). 2011 Dec 14;8:89. doi: 10.1186/1743-7075-8-89. Nutr Metab (Lond). 2011. PMID: 22168400 Free PMC article.

4

Lysophosphatidylcholine acyltransferase 3 knockdown-mediated liver lysophosphatidylcholine accumulation promotes very low density lipoprotein production by enhancing microsomal triglyceride transfer protein expression.

Li Z, Ding T, Pan X, Li Y, Li R, Sanders PE, Kuo MS, Hussain MM, Cao G, Jiang XC. Li Z, et al. Among authors: ding t. J Biol Chem. 2012 Jun 8;287(24):20122-31. doi: 10.1074/jbc.M111.334664. Epub 2012 Apr 17. J Biol Chem. 2012. PMID: 22511767 Free PMC article.

5

Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor γ2 suppression.

Li Y, Dong J, Ding T, Kuo MS, Cao G, Jiang XC, Li Z. Li Y, et al. Among authors: ding t. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1513-20. doi: 10.1161/ATVBAHA.113.301498. Epub 2013 May 2. Arterioscler Thromb Vasc Biol. 2013. PMID: 23640498 Free PMC article.

6

Pharmacologic inhibition of sphingomyelin synthase (SMS) activity reduces apolipoprotein-B secretion from hepatocytes and attenuates endotoxin-mediated macrophage inflammation.

Lou B, Dong J, Li Y, Ding T, Bi T, Li Y, Deng X, Ye D, Jiang XC. Lou B, et al. Among authors: ding t. PLoS One. 2014 Jul 17;9(7):e102641. doi: 10.1371/journal.pone.0102641. eCollection 2014. PLoS One. 2014. PMID: 25032960 Free PMC article.

7

All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity.

Ding T, Kabir I, Li Y, Lou C, Yazdanyar A, Xu J, Dong J, Zhou H, Park T, Boutjdir M, Li Z, Jiang XC. Ding T, et al. J Lipid Res. 2015 Mar;56(3):537-545. doi: 10.1194/jlr.M054627. Epub 2015 Jan 20. J Lipid Res. 2015. PMID: 25605874 Free PMC article.

8

Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors.

Li YL, Qi XY, Jiang H, Deng XD, Dong YP, Ding TB, Zhou L, Men P, Chu Y, Wang RX, Jiang XC, Ye DY. Li YL, et al. Bioorg Med Chem. 2015 Sep 15;23(18):6173-84. doi: 10.1016/j.bmc.2015.07.060. Epub 2015 Jul 30. Bioorg Med Chem. 2015. PMID: 26314925

9

Lysophosphatidylcholine acyltransferase 3 deficiency impairs 3T3L1 cell adipogenesis through activating Wnt/β-catenin pathway.

Feng C, Lou B, Dong J, Li Z, Chen Y, Li Y, Zhang X, Jiang XC, Ding T. Feng C, et al. Among authors: ding t. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug;1863(8):834-843. doi: 10.1016/j.bbalip.2018.04.008. Epub 2018 Apr 17. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29673706 Free PMC article.

10

2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity.

Lou B, Liu Q, Hou J, Kabir I, Liu P, Ding T, Dong J, Mo M, Ye D, Chen Y, Bui HH, Roth K, Cao Y, Jiang XC. Lou B, et al. Among authors: ding t. J Biol Chem. 2018 Nov 23;293(47):18328-18336. doi: 10.1074/jbc.RA118.005904. Epub 2018 Oct 10. J Biol Chem. 2018. PMID: 30305392 Free PMC article.

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