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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia.
Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A, Jeltsch M, Mitchell C, Alitalo K, Shima D, Betsholtz C. Gerhardt H, et al. Among authors: fruttiger m. J Cell Biol. 2003 Jun 23;161(6):1163-77. doi: 10.1083/jcb.200302047. Epub 2003 Jun 16. J Cell Biol. 2003. PMID: 12810700 Free PMC article.
Development of the retinal vasculature.
Fruttiger M. Fruttiger M. Angiogenesis. 2007;10(2):77-88. doi: 10.1007/s10456-007-9065-1. Epub 2007 Feb 24. Angiogenesis. 2007. PMID: 17322966 Review.
Wnt/beta-catenin signaling controls development of the blood-brain barrier.
Liebner S, Corada M, Bangsow T, Babbage J, Taddei A, Czupalla CJ, Reis M, Felici A, Wolburg H, Fruttiger M, Taketo MM, von Melchner H, Plate KH, Gerhardt H, Dejana E. Liebner S, et al. Among authors: fruttiger m. J Cell Biol. 2008 Nov 3;183(3):409-17. doi: 10.1083/jcb.200806024. Epub 2008 Oct 27. J Cell Biol. 2008. PMID: 18955553 Free PMC article.
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.
Tammela T, Zarkada G, Nurmi H, Jakobsson L, Heinolainen K, Tvorogov D, Zheng W, Franco CA, Murtomäki A, Aranda E, Miura N, Ylä-Herttuala S, Fruttiger M, Mäkinen T, Eichmann A, Pollard JW, Gerhardt H, Alitalo K. Tammela T, et al. Among authors: fruttiger m. Nat Cell Biol. 2011 Sep 11;13(10):1202-13. doi: 10.1038/ncb2331. Nat Cell Biol. 2011. PMID: 21909098 Free PMC article.
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Aspalter IM, Gordon E, Dubrac A, Ragab A, Narloch J, Vizán P, Geudens I, Collins RT, Franco CA, Abrahams CL, Thurston G, Fruttiger M, Rosewell I, Eichmann A, Gerhardt H. Aspalter IM, et al. Among authors: fruttiger m. Nat Commun. 2015 Jun 17;6:7264. doi: 10.1038/ncomms8264. Nat Commun. 2015. PMID: 26081042 Free PMC article.
138 results