Aoki Y - Search Results

1

Oligonucleotide-Based Therapy for FTD/ALS Caused by the C9orf72 Repeat Expansion: A Perspective.

Fernandes SA, Douglas AG, Varela MA, Wood MJ, Aoki Y. Fernandes SA, et al. Among authors: aoki y. J Nucleic Acids. 2013;2013:208245. doi: 10.1155/2013/208245. Epub 2013 Nov 17. J Nucleic Acids. 2013. PMID: 24349764 Free PMC article. Review.

2

Highly efficient in vivo delivery of PMO into regenerating myotubes and rescue in laminin-α2 chain-null congenital muscular dystrophy mice.

Aoki Y, Nagata T, Yokota T, Nakamura A, Wood MJ, Partridge T, Takeda S. Aoki Y, et al. Hum Mol Genet. 2013 Dec 15;22(24):4914-28. doi: 10.1093/hmg/ddt341. Epub 2013 Jul 23. Hum Mol Genet. 2013. PMID: 23882132 Free PMC article.

3

Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover.

Roberts TC, Godfrey C, McClorey G, Vader P, Briggs D, Gardiner C, Aoki Y, Sargent I, Morgan JE, Wood MJ. Roberts TC, et al. Among authors: aoki y. Nucleic Acids Res. 2013 Nov;41(20):9500-13. doi: 10.1093/nar/gkt724. Epub 2013 Aug 14. Nucleic Acids Res. 2013. PMID: 23945935 Free PMC article.

4

Development of multiexon skipping antisense oligonucleotide therapy for Duchenne muscular dystrophy.

Aoki Y, Yokota T, Wood MJ. Aoki Y, et al. Biomed Res Int. 2013;2013:402369. doi: 10.1155/2013/402369. Epub 2013 Jul 31. Biomed Res Int. 2013. PMID: 23984357 Free PMC article. Review.

5

Oligonucleotide therapies: the future of amyotrophic lateral sclerosis treatment?

Aoki Y, Douglas AG, Wood MJ. Aoki Y, et al. Neurodegener Dis Manag. 2015;5(2):93-5. doi: 10.2217/nmt.15.4. Neurodegener Dis Manag. 2015. PMID: 25894871 No abstract available.

6

Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides.

Ezzat K, Aoki Y, Koo T, McClorey G, Benner L, Coenen-Stass A, O'Donovan L, Lehto T, Garcia-Guerra A, Nordin J, Saleh AF, Behlke M, Morris J, Goyenvalle A, Dugovic B, Leumann C, Gordon S, Gait MJ, El-Andaloussi S, Wood MJ. Ezzat K, et al. Among authors: aoki y. Nano Lett. 2015 Jul 8;15(7):4364-73. doi: 10.1021/acs.nanolett.5b00490. Epub 2015 Jun 15. Nano Lett. 2015. PMID: 26042553 Free PMC article.

7

C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.

Aoki Y, Manzano R, Lee Y, Dafinca R, Aoki M, Douglas AGL, Varela MA, Sathyaprakash C, Scaber J, Barbagallo P, Vader P, Mäger I, Ezzat K, Turner MR, Ito N, Gasco S, Ohbayashi N, El Andaloussi S, Takeda S, Fukuda M, Talbot K, Wood MJA. Aoki Y, et al. Among authors: aoki m. Brain. 2017 Apr 1;140(4):887-897. doi: 10.1093/brain/awx024. Brain. 2017. PMID: 28334866

8

Peptide-conjugate antisense based splice-correction for Duchenne muscular dystrophy and other neuromuscular diseases.

Tsoumpra MK, Fukumoto S, Matsumoto T, Takeda S, Wood MJA, Aoki Y. Tsoumpra MK, et al. Among authors: aoki y. EBioMedicine. 2019 Jul;45:630-645. doi: 10.1016/j.ebiom.2019.06.036. Epub 2019 Jun 27. EBioMedicine. 2019. PMID: 31257147 Free PMC article. Review.

9

Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping.

Hara Y, Mizobe Y, Inoue YU, Hashimoto Y, Motohashi N, Masaki Y, Seio K, Takeda S, Nagata T, Wood MJA, Inoue T, Aoki Y. Hara Y, et al. Among authors: aoki y. Sci Rep. 2020 Jun 22;10(1):10110. doi: 10.1038/s41598-020-67077-4. Sci Rep. 2020. PMID: 32572084 Free PMC article.

10

Development of LNA Gapmer Oligonucleotide-Based Therapy for ALS/FTD Caused by the C9orf72 Repeat Expansion.

Sathyaprakash C, Manzano R, Varela MA, Hashimoto Y, Wood MJA, Talbot K, Aoki Y. Sathyaprakash C, et al. Among authors: aoki y. Methods Mol Biol. 2020;2176:185-208. doi: 10.1007/978-1-0716-0771-8_14. Methods Mol Biol. 2020. PMID: 32865792

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