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DLK1/PREF1 regulates nutrient metabolism and protects from steatosis.
Charalambous M, Da Rocha ST, Radford EJ, Medina-Gomez G, Curran S, Pinnock SB, Ferrón SR, Vidal-Puig A, Ferguson-Smith AC. Charalambous M, et al. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16088-93. doi: 10.1073/pnas.1406119111. Epub 2014 Oct 27. Proc Natl Acad Sci U S A. 2014. PMID: 25349437 Free PMC article.
Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction.
Cleaton MA, Dent CL, Howard M, Corish JA, Gutteridge I, Sovio U, Gaccioli F, Takahashi N, Bauer SR, Charnock-Jones DS, Powell TL, Smith GC, Ferguson-Smith AC, Charalambous M. Cleaton MA, et al. Among authors: charalambous m. Nat Genet. 2016 Dec;48(12):1473-1480. doi: 10.1038/ng.3699. Epub 2016 Oct 24. Nat Genet. 2016. PMID: 27776119 Free PMC article.
Imprinted gene dosage is critical for the transition to independent life.
Charalambous M, Ferron SR, da Rocha ST, Murray AJ, Rowland T, Ito M, Schuster-Gossler K, Hernandez A, Ferguson-Smith AC. Charalambous M, et al. Cell Metab. 2012 Feb 8;15(2):209-21. doi: 10.1016/j.cmet.2012.01.006. Cell Metab. 2012. PMID: 22326222 Free PMC article.
An unbiased assessment of the role of imprinted genes in an intergenerational model of developmental programming.
Radford EJ, Isganaitis E, Jimenez-Chillaron J, Schroeder J, Molla M, Andrews S, Didier N, Charalambous M, McEwen K, Marazzi G, Sassoon D, Patti ME, Ferguson-Smith AC. Radford EJ, et al. Among authors: charalambous m. PLoS Genet. 2012;8(4):e1002605. doi: 10.1371/journal.pgen.1002605. Epub 2012 Apr 12. PLoS Genet. 2012. PMID: 22511876 Free PMC article.
132 results