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Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling.
Pishas KI, Neuhaus SJ, Clayer MT, Schreiber AW, Lawrence DM, Perugini M, Whitfield RJ, Farshid G, Manavis J, Chryssidis S, Mayo BJ, Haycox RC, Ho K, Brown MP, D'Andrea RJ, Evdokiou A, Thomas DM, Desai J, Callen DF, Neilsen PM. Pishas KI, et al. Among authors: thomas dm. Cancer Res. 2014 Feb 1;74(3):921-31. doi: 10.1158/0008-5472.CAN-13-2424. Epub 2013 Dec 13. Cancer Res. 2014. PMID: 24336067
Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis.
Ito M, Barys L, O'Reilly T, Young S, Gorbatcheva B, Monahan J, Zumstein-Mecker S, Choong PF, Dickinson I, Crowe P, Hemmings C, Desai J, Thomas DM, Lisztwan J. Ito M, et al. Among authors: thomas dm. Clin Cancer Res. 2011 Feb 1;17(3):416-26. doi: 10.1158/1078-0432.CCR-10-2050. Epub 2010 Dec 15. Clin Cancer Res. 2011. PMID: 21159888
Targeting the p53 Pathway in Ewing Sarcoma.
Neilsen PM, Pishas KI, Callen DF, Thomas DM. Neilsen PM, et al. Among authors: thomas dm. Sarcoma. 2011;2011:746939. doi: 10.1155/2011/746939. Epub 2010 Dec 9. Sarcoma. 2011. PMID: 21197471 Free PMC article.
High frequency of germline TP53 mutations in a prospective adult-onset sarcoma cohort.
Mitchell G, Ballinger ML, Wong S, Hewitt C, James P, Young MA, Cipponi A, Pang T, Goode DL, Dobrovic A, Thomas DM; International Sarcoma Kindred Study. Mitchell G, et al. Among authors: thomas dm. PLoS One. 2013 Jul 22;8(7):e69026. doi: 10.1371/journal.pone.0069026. Print 2013. PLoS One. 2013. PMID: 23894400 Free PMC article.
527 results