Kirkby NS - Search Results

1

Evidence for the involvement of type I interferon in pulmonary arterial hypertension.

George PM, Oliver E, Dorfmuller P, Dubois OD, Reed DM, Kirkby NS, Mohamed NA, Perros F, Antigny F, Fadel E, Schreiber BE, Holmes AM, Southwood M, Hagan G, Wort SJ, Bartlett N, Morrell NW, Coghlan JG, Humbert M, Zhao L, Mitchell JA. George PM, et al. Among authors: kirkby ns. Circ Res. 2014 Feb 14;114(4):677-88. doi: 10.1161/CIRCRESAHA.114.302221. Epub 2013 Dec 13. Circ Res. 2014. PMID: 24334027 Free PMC article.

2

Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse.

Armstrong PC, Kirkby NS, Zain ZN, Emerson M, Mitchell JA, Warner TD. Armstrong PC, et al. Among authors: kirkby ns. PLoS One. 2011;6(5):e20062. doi: 10.1371/journal.pone.0020062. Epub 2011 May 23. PLoS One. 2011. PMID: 21629780 Free PMC article.

3

Aspirin has little additional anti-platelet effect in healthy volunteers receiving prasugrel.

Leadbeater PD, Kirkby NS, Thomas S, Dhanji AR, Tucker AT, Milne GL, Mitchell JA, Warner TD. Leadbeater PD, et al. Among authors: kirkby ns. J Thromb Haemost. 2011 Oct;9(10):2050-6. doi: 10.1111/j.1538-7836.2011.04450.x. J Thromb Haemost. 2011. PMID: 21794076 Free PMC article.

4

Short thromboelastography and the identification of high platelet reactivity while on and off therapy.

Warner TD, Mitchell JA, Kirkby NS. Warner TD, et al. Among authors: kirkby ns. Heart. 2012 May;98(9):679-80. doi: 10.1136/heartjnl-2012-301676. Heart. 2012. PMID: 22523052 No abstract available.

5

Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system.

Kirkby NS, Lundberg MH, Harrington LS, Leadbeater PD, Milne GL, Potter CM, Al-Yamani M, Adeyemi O, Warner TD, Mitchell JA. Kirkby NS, et al. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17597-602. doi: 10.1073/pnas.1209192109. Epub 2012 Oct 8. Proc Natl Acad Sci U S A. 2012. PMID: 23045674 Free PMC article.

6

Circulating microRNAs as novel biomarkers for platelet activation.

Willeit P, Zampetaki A, Dudek K, Kaudewitz D, King A, Kirkby NS, Crosby-Nwaobi R, Prokopi M, Drozdov I, Langley SR, Sivaprasad S, Markus HS, Mitchell JA, Warner TD, Kiechl S, Mayr M. Willeit P, et al. Among authors: kirkby ns. Circ Res. 2013 Feb 15;112(4):595-600. doi: 10.1161/CIRCRESAHA.111.300539. Epub 2013 Jan 2. Circ Res. 2013. PMID: 23283721

7

Cyclooxygenase and cytokine regulation in lung fibroblasts activated with viral versus bacterial pathogen associated molecular patterns.

Wright WR, Kirkby NS, Galloway-Phillipps NA, Reed DM, Paul-Clark MJ, Mitchell JA. Wright WR, et al. Among authors: kirkby ns. Prostaglandins Other Lipid Mediat. 2013 Dec;107:4-12. doi: 10.1016/j.prostaglandins.2013.05.006. Epub 2013 Jun 3. Prostaglandins Other Lipid Mediat. 2013. PMID: 23742950

8

Aspirin-triggered 15-epi-lipoxin A4 predicts cyclooxygenase-2 in the lungs of LPS-treated mice but not in the circulation: implications for a clinical test.

Kirkby NS, Chan MV, Lundberg MH, Massey KA, Edmands WM, MacKenzie LS, Holmes E, Nicolaou A, Warner TD, Mitchell JA. Kirkby NS, et al. FASEB J. 2013 Oct;27(10):3938-46. doi: 10.1096/fj.12-215533. Epub 2013 Jun 21. FASEB J. 2013. PMID: 23792301 Free PMC article.

9

Differential COX-2 induction by viral and bacterial PAMPs: Consequences for cytokine and interferon responses and implications for anti-viral COX-2 directed therapies.

Kirkby NS, Zaiss AK, Wright WR, Jiao J, Chan MV, Warner TD, Herschman HR, Mitchell JA. Kirkby NS, et al. Biochem Biophys Res Commun. 2013 Aug 23;438(2):249-56. doi: 10.1016/j.bbrc.2013.07.006. Epub 2013 Jul 11. Biochem Biophys Res Commun. 2013. PMID: 23850620 Free PMC article.

10

LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expression.

Kirkby NS, Zaiss AK, Urquhart P, Jiao J, Austin PJ, Al-Yamani M, Lundberg MH, MacKenzie LS, Warner TD, Nicolaou A, Herschman HR, Mitchell JA. Kirkby NS, et al. PLoS One. 2013 Jul 9;8(7):e69524. doi: 10.1371/journal.pone.0069524. Print 2013. PLoS One. 2013. PMID: 23874970 Free PMC article.

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