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SQSTM1 is a pathogenic target of 5q copy number gains in kidney cancer.
Li L, Shen C, Nakamura E, Ando K, Signoretti S, Beroukhim R, Cowley GS, Lizotte P, Liberzon E, Bair S, Root DE, Tamayo P, Tsherniak A, Cheng SC, Tabak B, Jacobsen A, Hakimi AA, Schultz N, Ciriello G, Sander C, Hsieh JJ, Kaelin WG Jr. Li L, et al. Among authors: nakamura e. Cancer Cell. 2013 Dec 9;24(6):738-50. doi: 10.1016/j.ccr.2013.10.025. Cancer Cell. 2013. PMID: 24332042 Free PMC article.
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase.
Chakraborty AA, Nakamura E, Qi J, Creech A, Jaffe JD, Paulk J, Novak JS, Nagulapalli K, McBrayer SK, Cowley GS, Pineda J, Song J, Wang YE, Carr SA, Root DE, Signoretti S, Bradner JE, Kaelin WG Jr. Chakraborty AA, et al. Among authors: nakamura e. Sci Transl Med. 2017 Jul 12;9(398):eaal5272. doi: 10.1126/scitranslmed.aal5272. Sci Transl Med. 2017. PMID: 28701475 Free PMC article.
CCL2 as a potential therapeutic target for clear cell renal cell carcinoma.
Arakaki R, Yamasaki T, Kanno T, Shibasaki N, Sakamoto H, Utsunomiya N, Sumiyoshi T, Shibuya S, Tsuruyama T, Nakamura E, Ogawa O, Kamba T. Arakaki R, et al. Among authors: nakamura e. Cancer Med. 2016 Oct;5(10):2920-2933. doi: 10.1002/cam4.886. Epub 2016 Sep 26. Cancer Med. 2016. PMID: 27666332 Free PMC article.
Functional and genomic characterization of patient-derived xenograft model to study the adaptation to mTORC1 inhibitor in clear cell renal cell carcinoma.
Sakamoto H, Yamasaki T, Sumiyoshi T, Takeda M, Shibasaki N, Utsunomiya N, Arakaki R, Akamatsu S, Kobayashi T, Inoue T, Kamba T, Nakamura E, Ogawa O. Sakamoto H, et al. Among authors: nakamura e. Cancer Med. 2021 Jan;10(1):119-134. doi: 10.1002/cam4.3578. Epub 2020 Oct 27. Cancer Med. 2021. PMID: 33107222 Free PMC article.
1,103 results