Vargo MA - Search Results

1

Exploring novel strategies for AIDS protozoal pathogens: α-helix mimetics targeting a key allosteric protein-protein interaction in C. hominis TS-DHFR.

Martucci WE, Rodriguez JM, Vargo MA, Marr M, Hamilton AD, Anderson KS. Martucci WE, et al. Among authors: vargo ma. Medchemcomm. 2013 Sep;4(9):10.1039/C3MD00141E. doi: 10.1039/C3MD00141E. Medchemcomm. 2013. PMID: 24324854 Free PMC article.

2

Disruption of the crossover helix impairs dihydrofolate reductase activity in the bifunctional enzyme TS-DHFR from Cryptosporidium hominis.

Vargo MA, Martucci WE, Anderson KS. Vargo MA, et al. Biochem J. 2009 Feb 1;417(3):757-64. doi: 10.1042/BJ20081247. Biochem J. 2009. PMID: 18851711 Free PMC article.

3

Novel non-active site inhibitor of Cryptosporidium hominis TS-DHFR identified by a virtual screen.

Martucci WE, Udier-Blagovic M, Atreya C, Babatunde O, Vargo MA, Jorgensen WL, Anderson KS. Martucci WE, et al. Among authors: vargo ma. Bioorg Med Chem Lett. 2009 Jan 15;19(2):418-23. doi: 10.1016/j.bmcl.2008.11.054. Epub 2008 Nov 20. Bioorg Med Chem Lett. 2009. PMID: 19059777 Free PMC article.

4

Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis.

Doan LT, Martucci WE, Vargo MA, Atreya CE, Anderson KS. Doan LT, et al. Among authors: vargo ma. Biochemistry. 2007 Jul 17;46(28):8379-91. doi: 10.1021/bi700531r. Epub 2007 Jun 20. Biochemistry. 2007. PMID: 17580969

5

Explaining an unusually fast parasitic enzyme: folate tail-binding residues dictate substrate positioning and catalysis in Cryptosporidium hominis thymidylate synthase.

Martucci WE, Vargo MA, Anderson KS. Martucci WE, et al. Among authors: vargo ma. Biochemistry. 2008 Aug 26;47(34):8902-11. doi: 10.1021/bi800466z. Epub 2008 Aug 2. Biochemistry. 2008. PMID: 18672899 Free PMC article.

6

First three-dimensional structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: insights for catalysis, interdomain interactions, and substrate channeling.

Sharma H, Landau MJ, Vargo MA, Spasov KA, Anderson KS. Sharma H, et al. Among authors: vargo ma. Biochemistry. 2013 Oct 15;52(41):7305-7317. doi: 10.1021/bi400576t. Epub 2013 Oct 3. Biochemistry. 2013. PMID: 24053355 Free PMC article.

7

Subunit interface residues of glutathione S-transferase A1-1 that are important in the monomer-dimer equilibrium.

Vargo MA, Nguyen L, Colman RF. Vargo MA, et al. Biochemistry. 2004 Mar 30;43(12):3327-35. doi: 10.1021/bi030245z. Biochemistry. 2004. PMID: 15035604

8

Chemical modification at subunit 1 of rat kidney Alpha class glutathione transferase with 2,3,5,6-tetrachloro-1,4-benzoquinone: close structural connectivity between glutathione conjugation activity and non-substrate ligand binding.

O'Sullivan SM, McCarthy RM, Vargo MA, Colman RF, Sheehan D. O'Sullivan SM, et al. Among authors: vargo ma. Biochem Pharmacol. 2006 May 28;71(11):1629-36. doi: 10.1016/j.bcp.2006.03.002. Epub 2006 Apr 18. Biochem Pharmacol. 2006. PMID: 16620786

9

Heterodimers of wild-type and subunit interface mutant enzymes of glutathione S-transferase A1-1: interactive or independent active sites?

Vargo MA, Colman RF. Vargo MA, et al. Protein Sci. 2004 Jun;13(6):1586-93. doi: 10.1110/ps.04694004. Protein Sci. 2004. PMID: 15152091 Free PMC article.

10

Affinity labeling of rat glutathione S-transferase isozyme 1-1 by 17beta -iodoacetoxy-estradiol-3-sulfate.

Vargo MA, Colman RF. Vargo MA, et al. J Biol Chem. 2001 Jan 19;276(3):2031-6. doi: 10.1074/jbc.M008212200. Epub 2000 Oct 12. J Biol Chem. 2001. PMID: 11031273 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

15 results

Search Page