Chai Y - Search Results

1

Structure-dependent binding of arylimidamides to the DNA minor groove.

Chai Y, Munde M, Kumar A, Mickelson L, Lin S, Campbell NH, Banerjee M, Akay S, Liu Z, Farahat AA, Nhili R, Depauw S, David-Cordonnier MH, Neidle S, Wilson WD, Boykin DW. Chai Y, et al. Chembiochem. 2014 Jan 3;15(1):68-79. doi: 10.1002/cbic.201300622. Epub 2013 Dec 9. Chembiochem. 2014. PMID: 24323836 Free PMC article.

2

Designed compounds for recognition of 10 base pairs of DNA with two at binding sites.

Liu Y, Chai Y, Kumar A, Tidwell RR, Boykin DW, Wilson WD. Liu Y, et al. Among authors: chai y. J Am Chem Soc. 2012 Mar 21;134(11):5290-9. doi: 10.1021/ja211628j. Epub 2012 Mar 9. J Am Chem Soc. 2012. PMID: 22369366 Free PMC article.

3

Design and synthesis of heterocyclic cations for specific DNA recognition: from AT-rich to mixed-base-pair DNA sequences.

Chai Y, Paul A, Rettig M, Wilson WD, Boykin DW. Chai Y, et al. J Org Chem. 2014 Feb 7;79(3):852-66. doi: 10.1021/jo402599s. Epub 2014 Jan 21. J Org Chem. 2014. PMID: 24422528 Free PMC article.

4

Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair.

Paul A, Nanjunda R, Kumar A, Laughlin S, Nhili R, Depauw S, Deuser SS, Chai Y, Chaudhary AS, David-Cordonnier MH, Boykin DW, Wilson WD. Paul A, et al. Among authors: chai y. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4927-4932. doi: 10.1016/j.bmcl.2015.05.005. Epub 2015 May 19. Bioorg Med Chem Lett. 2015. PMID: 26051649 Free PMC article.

5

Imino proton NMR guides the reprogramming of A•T specific minor groove binders for mixed base pair recognition.

Harika NK, Paul A, Stroeva E, Chai Y, Boykin DW, Germann MW, Wilson WD. Harika NK, et al. Among authors: chai y. Nucleic Acids Res. 2016 Jun 2;44(10):4519-27. doi: 10.1093/nar/gkw353. Epub 2016 Apr 29. Nucleic Acids Res. 2016. PMID: 27131382 Free PMC article.

6

Understanding mixed sequence DNA recognition by novel designed compounds: the kinetic and thermodynamic behavior of azabenzimidazole diamidines.

Paul A, Chai Y, Boykin DW, Wilson WD. Paul A, et al. Among authors: chai y. Biochemistry. 2015 Jan 20;54(2):577-87. doi: 10.1021/bi500989r. Epub 2014 Dec 24. Biochemistry. 2015. PMID: 25495885 Free PMC article.

7

Molecular modeling study and synthesis of novel dicationic flexible triaryl guanidines and imidamides as antiprotozoal agents.

Arafa RK, Wenzler T, Brun R, Chai Y, Wilson WD. Arafa RK, et al. Among authors: chai y. Eur J Med Chem. 2011 Dec;46(12):5852-60. doi: 10.1016/j.ejmech.2011.09.047. Epub 2011 Oct 2. Eur J Med Chem. 2011. PMID: 22005186

8

Conformational modulation of DNA by polyamide binding: structural effects of f-Im-Py-Im based derivatives on 5'-ACGCGT-3'.

Wang S, Chai Y, Babu B, Satam V, Lee M, David Wilson W. Wang S, et al. Among authors: chai y. J Mol Recognit. 2013 Aug;26(8):331-40. doi: 10.1002/jmr.2273. J Mol Recognit. 2013. PMID: 23784989 Free PMC article.

9

Time-course swRNA-seq uncovers a hierarchical gene regulatory network in controlling the response-repair-remodeling after wounding.

Yu X, Zhou J, Ye W, Xu J, Li R, Huang L, Chai Y, Wen M, Xu S, Zhou Y. Yu X, et al. Among authors: chai y. Commun Biol. 2024 Jun 6;7(1):694. doi: 10.1038/s42003-024-06352-w. Commun Biol. 2024. PMID: 38844830

10

Intraoperative neuromonitoring during thyroidectomy does not decrease vocal cord palsy risk, but the cumulative experience of the surgeon may.

Bae HL, Young M, Han M, Wu CW, Chai YJ. Bae HL, et al. Among authors: chai yj. Surg Today. 2024 Jun 6. doi: 10.1007/s00595-024-02871-5. Online ahead of print. Surg Today. 2024. PMID: 38842555

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