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Structure and enzymatic mechanism of a moonlighting dUTPase.
Leveles I, Németh V, Szabó JE, Harmat V, Nyíri K, Bendes ÁÁ, Papp-Kádár V, Zagyva I, Róna G, Ozohanics O, Vékey K, Tóth J, Vértessy BG. Leveles I, et al. Among authors: zagyva i. Acta Crystallogr D Biol Crystallogr. 2013 Dec;69(Pt 12):2298-308. doi: 10.1107/S0907444913021136. Epub 2013 Nov 19. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 24311572
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control.
Szabó JE, Németh V, Papp-Kádár V, Nyíri K, Leveles I, Bendes AÁ, Zagyva I, Róna G, Pálinkás HL, Besztercei B, Ozohanics O, Vékey K, Liliom K, Tóth J, Vértessy BG. Szabó JE, et al. Among authors: zagyva i. Nucleic Acids Res. 2014 Oct 29;42(19):11912-20. doi: 10.1093/nar/gku882. Epub 2014 Oct 1. Nucleic Acids Res. 2014. PMID: 25274731 Free PMC article.
Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.
Kovári J, Barabás O, Takács E, Békési A, Dubrovay Z, Pongrácz V, Zagyva I, Imre T, Szabó P, Vértessy BG. Kovári J, et al. Among authors: zagyva i. J Biol Chem. 2004 Apr 23;279(17):17932-44. doi: 10.1074/jbc.M313643200. Epub 2004 Jan 14. J Biol Chem. 2004. PMID: 14724274 Free article.
Developmental regulation of dUTPase in Drosophila melanogaster.
Békési A, Zagyva I, Hunyadi-Gulyás E, Pongrácz V, Kovári J, Nagy AO, Erdei A, Medzihradszky KF, Vértessy BG. Békési A, et al. Among authors: zagyva i. J Biol Chem. 2004 May 21;279(21):22362-70. doi: 10.1074/jbc.M313647200. Epub 2004 Mar 2. J Biol Chem. 2004. PMID: 14996835 Free article.
Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling.
Barabás O, Németh V, Bodor A, Perczel A, Rosta E, Kele Z, Zagyva I, Szabadka Z, Grolmusz VI, Wilmanns M, Vértessy BG. Barabás O, et al. Among authors: zagyva i. Nucleic Acids Res. 2013 Dec;41(22):10542-55. doi: 10.1093/nar/gkt756. Epub 2013 Aug 27. Nucleic Acids Res. 2013. PMID: 23982515 Free PMC article.
A novel fruitfly protein under developmental control degrades uracil-DNA.
Békési A, Pukáncsik M, Muha V, Zagyva I, Leveles I, Hunyadi-Gulyás E, Klement E, Medzihradszky KF, Kele Z, Erdei A, Felföldi F, Kónya E, Vértessy BG. Békési A, et al. Among authors: zagyva i. Biochem Biophys Res Commun. 2007 Apr 13;355(3):643-8. doi: 10.1016/j.bbrc.2007.01.196. Epub 2007 Feb 12. Biochem Biophys Res Commun. 2007. PMID: 17306761
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