Pérez-Chacón G - Search Results

1

Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma.

Somovilla-Crespo B, Alfonso-Pérez M, Cuesta-Mateos C, Carballo-de Dios C, Beltrán AE, Terrón F, Pérez-Villar JJ, Gamallo-Amat C, Pérez-Chacón G, Fernández-Ruiz E, Zapata JM, Muñoz-Calleja C. Somovilla-Crespo B, et al. J Hematol Oncol. 2013 Dec 4;6:89. doi: 10.1186/1756-8722-6-89. J Hematol Oncol. 2013. PMID: 24305507 Free PMC article.

2

TNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.

Pérez-Chacón G, Llobet D, Pardo C, Pindado J, Choi Y, Reed JC, Zapata JM. Pérez-Chacón G, et al. J Immunol. 2012 Jul 15;189(2):1053-61. doi: 10.4049/jimmunol.1200814. Epub 2012 Jun 18. J Immunol. 2012. PMID: 22711886 Free PMC article.

3

T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.

Martinez-Forero I, Azpilikueta A, Bolaños-Mateo E, Nistal-Villan E, Palazon A, Teijeira A, Perez-Chacon G, Morales-Kastresana A, Murillo O, Jure-Kunkel M, Zapata JM, Melero I. Martinez-Forero I, et al. J Immunol. 2013 Jun 15;190(12):6694-706. doi: 10.4049/jimmunol.1203010. Epub 2013 May 20. J Immunol. 2013. PMID: 23690480

4

Indole-3-carbinol induces cMYC and IAP-family downmodulation and promotes apoptosis of Epstein-Barr virus (EBV)-positive but not of EBV-negative Burkitt's lymphoma cell lines.

Perez-Chacon G, de Los Rios C, Zapata JM. Perez-Chacon G, et al. Pharmacol Res. 2014 Nov;89:46-56. doi: 10.1016/j.phrs.2014.08.005. Epub 2014 Aug 30. Pharmacol Res. 2014. PMID: 25180456 Free article.

5

Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances.

Perez-Chacon G, Martinez-Laperche C, Rebolleda N, Somovilla-Crespo B, Muñoz-Calleja C, Buño I, Zapata JM. Perez-Chacon G, et al. Clin Cancer Res. 2016 Jan 1;22(1):134-45. doi: 10.1158/1078-0432.CCR-15-0736. Epub 2015 Aug 31. Clin Cancer Res. 2016. PMID: 26324744

6

Efficient expression of bioactive murine IL12 as a self-processing P2A polypeptide driven by inflammation-regulated promoters in tumor cell lines.

Lorenzo C, Pérez-Chacón G, Garaulet G, Mallorquín Z, Zapata JM, Rodríguez A. Lorenzo C, et al. Cancer Gene Ther. 2015 Nov;22(11):542-51. doi: 10.1038/cgt.2015.53. Epub 2015 Oct 9. Cancer Gene Ther. 2015. PMID: 26450626

7

Fludarabine Inhibits K_V1.3 Currents in Human B Lymphocytes.

de la Cruz A, Vera-Zambrano A, Peraza DA, Valenzuela C, Zapata JM, Perez-Chacon G, Gonzalez T. de la Cruz A, et al. Front Pharmacol. 2017 Mar 31;8:177. doi: 10.3389/fphar.2017.00177. eCollection 2017. Front Pharmacol. 2017. PMID: 28408885 Free PMC article.

8

Bioconjugation through Mesitylene Thiol Alkylation.

Ramos-Tomillero I, Perez-Chacon G, Somovilla-Crespo B, Sanchez-Madrid F, Domínguez JM, Cuevas C, Zapata JM, Rodríguez H, Albericio F. Ramos-Tomillero I, et al. Bioconjug Chem. 2018 Apr 18;29(4):1199-1208. doi: 10.1021/acs.bioconjchem.7b00828. Epub 2018 Mar 6. Bioconjug Chem. 2018. PMID: 29433317

9

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity.

Compte M, Harwood SL, Muñoz IG, Navarro R, Zonca M, Perez-Chacon G, Erce-Llamazares A, Merino N, Tapia-Galisteo A, Cuesta AM, Mikkelsen K, Caleiras E, Nuñez-Prado N, Aznar MA, Lykkemark S, Martínez-Torrecuadrada J, Melero I, Blanco FJ, Bernardino de la Serna J, Zapata JM, Sanz L, Alvarez-Vallina L. Compte M, et al. Nat Commun. 2018 Nov 15;9(1):4809. doi: 10.1038/s41467-018-07195-w. Nat Commun. 2018. PMID: 30442944 Free PMC article.

10

CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs.

Zapata JM, Perez-Chacon G, Carr-Baena P, Martinez-Forero I, Azpilikueta A, Otano I, Melero I. Zapata JM, et al. Front Immunol. 2018 Nov 15;9:2618. doi: 10.3389/fimmu.2018.02618. eCollection 2018. Front Immunol. 2018. PMID: 30524423 Free PMC article. Review.

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