Kardar M - Search Results

1

The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.

Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P. Sok D, et al. Among authors: kardar m. PLoS Pathog. 2013;9(11):e1003754. doi: 10.1371/journal.ppat.1003754. Epub 2013 Nov 21. PLoS Pathog. 2013. PMID: 24278016 Free PMC article. Clinical Trial.

2

Effective membrane model of the immunological synapse.

Raychaudhuri S, Chakraborty AK, Kardar M. Raychaudhuri S, et al. Among authors: kardar m. Phys Rev Lett. 2003 Nov 14;91(20):208101. doi: 10.1103/PhysRevLett.91.208101. Epub 2003 Nov 10. Phys Rev Lett. 2003. PMID: 14683399

3

Purely stochastic binary decisions in cell signaling models without underlying deterministic bistabilities.

Artyomov MN, Das J, Kardar M, Chakraborty AK. Artyomov MN, et al. Among authors: kardar m. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18958-63. doi: 10.1073/pnas.0706110104. Epub 2007 Nov 19. Proc Natl Acad Sci U S A. 2007. PMID: 18025473 Free PMC article.

4

Positive feedback regulation results in spatial clustering and fast spreading of active signaling molecules on a cell membrane.

Das J, Kardar M, Chakraborty AK. Das J, et al. Among authors: kardar m. J Chem Phys. 2009 Jun 28;130(24):245102. doi: 10.1063/1.3149861. J Chem Phys. 2009. PMID: 19566183 Free PMC article.

5

Thymic selection of T-cell receptors as an extreme value problem.

Kosmrlj A, Chakraborty AK, Kardar M, Shakhnovich EI. Kosmrlj A, et al. Among authors: kardar m. Phys Rev Lett. 2009 Aug 7;103(6):068103. doi: 10.1103/PhysRevLett.103.068103. Epub 2009 Aug 7. Phys Rev Lett. 2009. PMID: 19792616

6

Only signaling modules that discriminate sharply between stimulatory and nonstimulatory inputs require basal signaling for fast cellular responses.

Artomov M, Kardar M, Chakraborty AK. Artomov M, et al. Among authors: kardar m. J Chem Phys. 2010 Sep 14;133(10):105101. doi: 10.1063/1.3482813. J Chem Phys. 2010. PMID: 20849190 Free PMC article.

7

Quorum sensing allows T cells to discriminate between self and nonself.

Butler TC, Kardar M, Chakraborty AK. Butler TC, et al. Among authors: kardar m. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11833-8. doi: 10.1073/pnas.1222467110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818603 Free PMC article.

8

Spin models inferred from patient-derived viral sequence data faithfully describe HIV fitness landscapes.

Shekhar K, Ruberman CF, Ferguson AL, Barton JP, Kardar M, Chakraborty AK. Shekhar K, et al. Among authors: kardar m. Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Dec;88(6):062705. doi: 10.1103/PhysRevE.88.062705. Epub 2013 Dec 4. Phys Rev E Stat Nonlin Soft Matter Phys. 2013. PMID: 24483484 Free PMC article.

9

Scaling laws describe memories of host-pathogen riposte in the HIV population.

Barton JP, Kardar M, Chakraborty AK. Barton JP, et al. Among authors: kardar m. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):1965-70. doi: 10.1073/pnas.1415386112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646424 Free PMC article.

10

Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodies.

Wang S, Mata-Fink J, Kriegsman B, Hanson M, Irvine DJ, Eisen HN, Burton DR, Wittrup KD, Kardar M, Chakraborty AK. Wang S, et al. Among authors: kardar m. Cell. 2015 Feb 12;160(4):785-797. doi: 10.1016/j.cell.2015.01.027. Epub 2015 Feb 5. Cell. 2015. PMID: 25662010 Free PMC article.

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