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Chutes and ladders in hepatitis C nucleoside drug development.
Coats SJ, Garnier-Amblard EC, Amblard F, Ehteshami M, Amiralaei S, Zhang H, Zhou L, Boucle SR, Lu X, Bondada L, Shelton JR, Li H, Liu P, Li C, Cho JH, Chavre SN, Zhou S, Mathew J, Schinazi RF. Coats SJ, et al. Among authors: zhou s, zhou l. Antiviral Res. 2014 Feb;102:119-47. doi: 10.1016/j.antiviral.2013.11.008. Epub 2013 Nov 23. Antiviral Res. 2014. PMID: 24275341 Free PMC article. Review.
2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.
Zhou S, Mahmoud S, Liu P, Zhou L, Ehteshami M, Bassit L, Tao S, Domaoal RA, Sari O, Schutter C, Amiralaei S, Khalil A, Ollinger Russell O, McBrayer T, Whitaker T, Abou-Taleb N, Amblard F, Coats SJ, Schinazi RF. Zhou S, et al. Among authors: zhou l. J Med Chem. 2017 Jul 13;60(13):5424-5437. doi: 10.1021/acs.jmedchem.7b00067. Epub 2017 Jun 26. J Med Chem. 2017. PMID: 28595015
Structural and Antiviral Studies of the Human Norovirus GII.4 Protease.
Muzzarelli KM, Kuiper B, Spellmon N, Brunzelle J, Hackett J, Amblard F, Zhou S, Liu P, Kovari IA, Yang Z, Schinazi RF, Kovari LC. Muzzarelli KM, et al. Among authors: zhou s. Biochemistry. 2019 Feb 19;58(7):900-907. doi: 10.1021/acs.biochem.8b01063. Epub 2019 Jan 16. Biochemistry. 2019. PMID: 30605321 Free PMC article.
Synthesis and anti-HCV activity of β-d-2'-deoxy-2'-α-chloro-2'-β-fluoro and β-d-2'-deoxy-2'-α-bromo-2'-β-fluoro nucleosides and their phosphoramidate prodrugs.
Ovadia R, Khalil A, Li H, De Schutter C, Mengshetti S, Zhou S, Bassit L, Coats SJ, Amblard F, Schinazi RF. Ovadia R, et al. Among authors: zhou s. Bioorg Med Chem. 2019 Feb 15;27(4):664-676. doi: 10.1016/j.bmc.2019.01.005. Epub 2019 Jan 9. Bioorg Med Chem. 2019. PMID: 30655167 Free PMC article.
Intracellular metabolism and potential cardiotoxicity of a β-D-2'-C-methyl-2,6-diaminopurine ribonucleoside phosphoramidate that inhibits hepatitis C virus replication.
Tao S, Zhou L, Zhang H, Zhou S, Amiralaei S, Shelton J, Ehteshami M, Jiang Y, Amblard F, Coats SJ, Schinazi RF. Tao S, et al. Among authors: zhou s, zhou l. Nucleosides Nucleotides Nucleic Acids. 2020;39(1-3):204-224. doi: 10.1080/15257770.2019.1671594. Epub 2019 Oct 9. Nucleosides Nucleotides Nucleic Acids. 2020. PMID: 31595843 Free PMC article.
Synthesis and evaluation of highly potent HBV capsid assembly modulators (CAMs).
Amblard F, Chen Z, Wiseman J, Zhou S, Liu P, Salman M, Verma K, Azadi N, Downs-Bowen J, Tao S, Kumari A, Zhang Q, Smith DB, Patel D, Bassit L, Schinazi RF. Amblard F, et al. Among authors: zhou s. Bioorg Chem. 2023 Dec;141:106923. doi: 10.1016/j.bioorg.2023.106923. Epub 2023 Oct 20. Bioorg Chem. 2023. PMID: 37871391
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