Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Search Results
8 results
Filters applied: . Clear all
Results are displayed in a computed author sort order.
The Results By Year timeline is not available.
Page 1
Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonists.
Bioorg Med Chem Lett. 2013 Dec 15;23(24):6890-6. doi: 10.1016/j.bmcl.2013.09.090. Epub 2013 Oct 5.
Bioorg Med Chem Lett. 2013.
PMID: 24269482
4-acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a novel class of non-brain-penetrant histamine H3 receptor antagonists.
Procopiou PA, Ancliff RA, Bamford MJ, Browning C, Connor H, Davies S, Fogden YC, Hodgson ST, Holmes DS, Looker BE, Morriss KM, Parr CA, Pickup EA, Sehmi SS, White GV, Watts CJ, Wilson DM, Woodrow MD.
Procopiou PA, et al. Among authors: sehmi ss.
J Med Chem. 2007 Dec 27;50(26):6706-17. doi: 10.1021/jm0708228. Epub 2007 Dec 6.
J Med Chem. 2007.
PMID: 18052318
Item in Clipboard
The discovery of the benzazepine class of histamine H3 receptor antagonists.
Wilson DM, Apps J, Bailey N, Bamford MJ, Beresford IJ, Briggs MA, Calver AR, Crook B, Davis RP, Davis S, Dean DK, Harris L, Heightman TD, Panchal T, Parr CA, Quashie N, Steadman JG, Schogger J, Sehmi SS, Stean TO, Takle AK, Trail BK, White T, Witherington J, Worby A, Medhurst AD.
Wilson DM, et al. Among authors: sehmi ss.
Bioorg Med Chem Lett. 2013 Dec 15;23(24):6897-901. doi: 10.1016/j.bmcl.2013.09.089. Epub 2013 Oct 5.
Bioorg Med Chem Lett. 2013.
PMID: 24161834
Item in Clipboard
(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: further optimisation as highly potent and selective MSK-1-inhibitors.
Bamford MJ, Bailey N, Davies S, Dean DK, Francis L, Panchal TA, Parr CA, Sehmi S, Steadman JG, Takle AK, Townsend JT, Wilson DM.
Bamford MJ, et al.
Bioorg Med Chem Lett. 2005 Jul 15;15(14):3407-11. doi: 10.1016/j.bmcl.2005.05.020.
Bioorg Med Chem Lett. 2005.
PMID: 15955699
Item in Clipboard
Potent oxadiazole CGRP receptor antagonists for the potential treatment of migraine.
Nichols PL, Brand J, Briggs M, D'Angeli M, Farge J, Garland SL, Goldsmith P, Hutchings R, Kilford I, Li HY, MacPherson D, Nimmo F, Sanderson FD, Sehmi S, Shuker N, Skidmore J, Stott M, Sweeting J, Tajuddin H, Takle AK, Trani G, Wall ID, Ward R, Wilson DM, Witty D.
Nichols PL, et al.
Bioorg Med Chem Lett. 2010 Feb 15;20(4):1368-72. doi: 10.1016/j.bmcl.2010.01.012. Epub 2010 Jan 11.
Bioorg Med Chem Lett. 2010.
PMID: 20097071
Item in Clipboard
Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease.
Spencer JP, Brown JT, Richardson JC, Medhurst AD, Sehmi SS, Calver AR, Randall AD.
Spencer JP, et al. Among authors: sehmi ss.
Neuroscience. 2004;129(1):49-54. doi: 10.1016/j.neuroscience.2004.06.070.
Neuroscience. 2004.
PMID: 15489027
Item in Clipboard
Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.
Skidmore J, Atcha Z, Boucherat E, Castelletti L, Chen DW, Coppo FT, Cutler L, Dunsdon RM, Heath BM, Hutchings R, Hurst DN, Javed S, Martin S, Maskell ES, Norton D, Pemberton DJ, Redshaw S, Rutter R, Sehmi SS, Scoccitti T, Temple HE, Theobald P, Ward RW, Wilson DM.
Skidmore J, et al. Among authors: sehmi ss.
Bioorg Med Chem Lett. 2012 May 15;22(10):3560-3. doi: 10.1016/j.bmcl.2012.03.040. Epub 2012 Mar 16.
Bioorg Med Chem Lett. 2012.
PMID: 22503248
Item in Clipboard
The discovery of 2-fluoro-N-(3-fluoro-4-(5-((4-morpholinobutyl)amino)-1,3,4-oxadiazol-2-yl)phenyl)benzamide, a full agonist of the alpha-7 nicotinic acetylcholine receptor showing efficacy in the novel object recognition model of cognition enhancement.
Skidmore J, Atcha Z, Boucherat E, Castelletti L, Chen DW, Coppo FT, Cutler L, Dunsdon RM, Heath BM, Hutchings R, Hurst DN, Javed S, Martin S, Maskell ES, Norton D, Pemberton DJ, Redshaw S, Rutter R, Sehmi SS, Scoccitti T, Temple HE, Theobald P, Ward RW, Wilson DM.
Skidmore J, et al. Among authors: sehmi ss.
Bioorg Med Chem Lett. 2012 May 15;22(10):3531-4. doi: 10.1016/j.bmcl.2012.03.062. Epub 2012 Mar 21.
Bioorg Med Chem Lett. 2012.
PMID: 22503453
Item in Clipboard
Cite
Cite