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Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors.
Cell Rep. 2013 Nov 27;5(4):1047-59. doi: 10.1016/j.celrep.2013.10.038. Epub 2013 Nov 21.
Cell Rep. 2013.
PMID: 24268771
Free PMC article.
Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737.
Wiegmans AP, Alsop AE, Bots M, Cluse LA, Williams SP, Banks KM, Ralli R, Scott CL, Frenzel A, Villunger A, Johnstone RW.
Wiegmans AP, et al.
Cancer Res. 2011 May 15;71(10):3603-15. doi: 10.1158/0008-5472.CAN-10-3289. Epub 2011 Mar 11.
Cancer Res. 2011.
PMID: 21398407
Free article.
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Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Shortt J, Martin BP, Newbold A, Hannan KM, Devlin JR, Baker AJ, Ralli R, Cullinane C, Schmitt CA, Reimann M, Hall MN, Wall M, Hannan RD, Pearson RB, McArthur GA, Johnstone RW.
Shortt J, et al.
Blood. 2013 Apr 11;121(15):2964-74. doi: 10.1182/blood-2012-08-446096. Epub 2013 Feb 12.
Blood. 2013.
PMID: 23403624
Free PMC article.
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Histone deacetylase inhibitors are unable to synergize with ABT-737 in killing primary chronic lymphocytic leukaemia cells in vitro.
Ralli R, Banks KM, Wiegmans AP, Carney D, Seymour JF, Johnstone RW, Alsop AE.
Ralli R, et al.
Leukemia. 2012 Jun;26(6):1433-5. doi: 10.1038/leu.2011.370. Epub 2012 Jan 6.
Leukemia. 2012.
PMID: 22289920
No abstract available.
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Mitotic arrest in teratoma susceptible fetal male germ cells.
Western PS, Ralli RA, Wakeling SI, Lo C, van den Bergen JA, Miles DC, Sinclair AH.
Western PS, et al. Among authors: ralli ra.
PLoS One. 2011;6(6):e20736. doi: 10.1371/journal.pone.0020736. Epub 2011 Jun 2.
PLoS One. 2011.
PMID: 21674058
Free PMC article.
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