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TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity.
Moudry P, Watanabe K, Wolanin KM, Bartkova J, Wassing IE, Watanabe S, Strauss R, Troelsgaard Pedersen R, Oestergaard VH, Lisby M, Andújar-Sánchez M, Maya-Mendoza A, Esashi F, Lukas J, Bartek J. Moudry P, et al. Among authors: lukas j. J Cell Biol. 2016 Feb 1;212(3):281-8. doi: 10.1083/jcb.201507042. Epub 2016 Jan 25. J Cell Biol. 2016. PMID: 26811421 Free PMC article.
Chk1 and Chk2 kinases in checkpoint control and cancer.
Bartek J, Lukas J. Bartek J, et al. Among authors: lukas j. Cancer Cell. 2003 May;3(5):421-9. doi: 10.1016/s1535-6108(03)00110-7. Cancer Cell. 2003. PMID: 12781359 Free article. Review.
Checking on DNA damage in S phase.
Bartek J, Lukas C, Lukas J. Bartek J, et al. Among authors: lukas j, lukas c. Nat Rev Mol Cell Biol. 2004 Oct;5(10):792-804. doi: 10.1038/nrm1493. Nat Rev Mol Cell Biol. 2004. PMID: 15459660 Review.
HCLK2 is required for activity of the DNA damage response kinase ATR.
Rendtlew Danielsen JM, Larsen DH, Schou KB, Freire R, Falck J, Bartek J, Lukas J. Rendtlew Danielsen JM, et al. Among authors: lukas j. J Biol Chem. 2009 Feb 13;284(7):4140-7. doi: 10.1074/jbc.M808174200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19097996 Free article.
510 results