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146 results

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Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.
Dawson MA, Gudgin EJ, Horton SJ, Giotopoulos G, Meduri E, Robson S, Cannizzaro E, Osaki H, Wiese M, Putwain S, Fong CY, Grove C, Craig J, Dittmann A, Lugo D, Jeffrey P, Drewes G, Lee K, Bullinger L, Prinjha RK, Kouzarides T, Vassiliou GS, Huntly BJ. Dawson MA, et al. Leukemia. 2014 Feb;28(2):311-20. doi: 10.1038/leu.2013.338. Epub 2013 Nov 13. Leukemia. 2014. PMID: 24220271 Free PMC article.
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, Chan WI, Robson SC, Chung CW, Hopf C, Savitski MM, Huthmacher C, Gudgin E, Lugo D, Beinke S, Chapman TD, Roberts EJ, Soden PE, Auger KR, Mirguet O, Doehner K, Delwel R, Burnett AK, Jeffrey P, Drewes G, Lee K, Huntly BJ, Kouzarides T. Dawson MA, et al. Nature. 2011 Oct 2;478(7370):529-33. doi: 10.1038/nature10509. Nature. 2011. PMID: 21964340 Free PMC article.
Cancer epigenetics: from mechanism to therapy.
Dawson MA, Kouzarides T. Dawson MA, et al. Cell. 2012 Jul 6;150(1):12-27. doi: 10.1016/j.cell.2012.06.013. Cell. 2012. PMID: 22770212 Free article. Review.
Targeting epigenetic readers in cancer.
Dawson MA, Kouzarides T, Huntly BJ. Dawson MA, et al. N Engl J Med. 2012 Aug 16;367(7):647-57. doi: 10.1056/NEJMra1112635. N Engl J Med. 2012. PMID: 22894577 Review. No abstract available.
Three distinct patterns of histone H3Y41 phosphorylation mark active genes.
Dawson MA, Foster SD, Bannister AJ, Robson SC, Hannah R, Wang X, Xhemalce B, Wood AD, Green AR, Göttgens B, Kouzarides T. Dawson MA, et al. Cell Rep. 2012 Sep 27;2(3):470-7. doi: 10.1016/j.celrep.2012.08.016. Epub 2012 Sep 20. Cell Rep. 2012. PMID: 22999934 Free PMC article.
Bromodomains as therapeutic targets in cancer.
Barbieri I, Cannizzaro E, Dawson MA. Barbieri I, et al. Among authors: dawson ma. Brief Funct Genomics. 2013 May;12(3):219-30. doi: 10.1093/bfgp/elt007. Epub 2013 Mar 28. Brief Funct Genomics. 2013. PMID: 23543289 Review.
BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms.
Wyspiańska BS, Bannister AJ, Barbieri I, Nangalia J, Godfrey A, Calero-Nieto FJ, Robson S, Rioja I, Li J, Wiese M, Cannizzaro E, Dawson MA, Huntly B, Prinjha RK, Green AR, Gottgens B, Kouzarides T. Wyspiańska BS, et al. Among authors: dawson ma. Leukemia. 2014 Jan;28(1):88-97. doi: 10.1038/leu.2013.234. Epub 2013 Aug 9. Leukemia. 2014. PMID: 23929215
146 results