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Evidence that duplications of 22q11.2 protect against schizophrenia.
Rees E, Kirov G, Sanders A, Walters JT, Chambert KD, Shi J, Szatkiewicz J, O'Dushlaine C, Richards AL, Green EK, Jones I, Davies G, Legge SE, Moran JL, Pato C, Pato M, Genovese G, Levinson D, Duan J, Moy W, Göring HH, Morris D, Cormican P, Kendler KS, O'Neill FA, Riley B, Gill M, Corvin A; Wellcome Trust Case Control Consortium; Craddock N, Sklar P, Hultman C, Sullivan PF, Gejman PV, McCarroll SA, O'Donovan MC, Owen MJ. Rees E, et al. Among authors: craddock n. Mol Psychiatry. 2014 Jan;19(1):37-40. doi: 10.1038/mp.2013.156. Epub 2013 Nov 12. Mol Psychiatry. 2014. PMID: 24217254 Free PMC article.
Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22.
Lambert D, Middle F, Hamshere ML, Segurado R, Raybould R, Corvin A, Green E, O'Mahony E, Nikolov I, Mulcahy T, Haque S, Bort S, Bennett P, Norton N, Owen MJ, Kirov G, Lendon C, Jones L, Jones I, Holmans P, Gill M, Craddock N. Lambert D, et al. Among authors: craddock n. Mol Psychiatry. 2005 Sep;10(9):831-41. doi: 10.1038/sj.mp.4001684. Mol Psychiatry. 2005. PMID: 15940300
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
Moskvina V, Craddock N, Holmans P, Nikolov I, Pahwa JS, Green E; Wellcome Trust Case Control Consortium; Owen MJ, O'Donovan MC. Moskvina V, et al. Among authors: craddock n. Mol Psychiatry. 2009 Mar;14(3):252-60. doi: 10.1038/mp.2008.133. Epub 2008 Dec 9. Mol Psychiatry. 2009. PMID: 19065143 Free PMC article.
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.
Green EK, Grozeva D, Jones I, Jones L, Kirov G, Caesar S, Gordon-Smith K, Fraser C, Forty L, Russell E, Hamshere ML, Moskvina V, Nikolov I, Farmer A, McGuffin P; Wellcome Trust Case Control Consortium; Holmans PA, Owen MJ, O'Donovan MC, Craddock N. Green EK, et al. Among authors: craddock n. Mol Psychiatry. 2010 Oct;15(10):1016-22. doi: 10.1038/mp.2009.49. Epub 2009 Jul 21. Mol Psychiatry. 2010. PMID: 19621016 Free PMC article.
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha.
Carroll LS, Williams NM, Moskvina V, Russell E, Norton N, Williams HJ, Peirce T, Georgieva L, Dwyer S, Grozeva D, Greene E, Farmer A, McGuffin P, Morris DW, Corvin A, Gill M, Rujescu D, Sham P, Holmans P, Jones I, Kirov G, Craddock N, O'Donovan MC, Owen MJ. Carroll LS, et al. Among authors: craddock n. Mol Psychiatry. 2010 Nov;15(11):1101-11. doi: 10.1038/mp.2009.96. Epub 2009 Sep 29. Mol Psychiatry. 2010. PMID: 19786960
Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder.
Williams HJ, Norton N, Dwyer S, Moskvina V, Nikolov I, Carroll L, Georgieva L, Williams NM, Morris DW, Quinn EM, Giegling I, Ikeda M, Wood J, Lencz T, Hultman C, Lichtenstein P, Thiselton D, Maher BS; Molecular Genetics of Schizophrenia Collaboration (MGS) International Schizophrenia Consortium (ISC), SGENE-plus, GROUP; Malhotra AK, Riley B, Kendler KS, Gill M, Sullivan P, Sklar P, Purcell S, Nimgaonkar VL, Kirov G, Holmans P, Corvin A, Rujescu D, Craddock N, Owen MJ, O'Donovan MC. Williams HJ, et al. Among authors: craddock n. Mol Psychiatry. 2011 Apr;16(4):429-41. doi: 10.1038/mp.2010.36. Epub 2010 Apr 6. Mol Psychiatry. 2011. PMID: 20368704 Free PMC article.
Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain.
Richards AL, Jones L, Moskvina V, Kirov G, Gejman PV, Levinson DF, Sanders AR; Molecular Genetics of Schizophrenia Collaboration (MGS); International Schizophrenia Consortium (ISC); Purcell S, Visscher PM, Craddock N, Owen MJ, Holmans P, O'Donovan MC. Richards AL, et al. Among authors: craddock n. Mol Psychiatry. 2012 Feb;17(2):193-201. doi: 10.1038/mp.2011.11. Epub 2011 Feb 22. Mol Psychiatry. 2012. PMID: 21339752 Free PMC article.
562 results