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Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.
Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB. Moreira DR, et al. Among authors: da silva ac, da cruz lf. ChemMedChem. 2014 Jan;9(1):177-88. doi: 10.1002/cmdc.201300354. Epub 2013 Nov 7. ChemMedChem. 2014. PMID: 24203393
Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.
Magalhaes Moreira DR, de Oliveira AD, Teixeira de Moraes Gomes PA, de Simone CA, Villela FS, Ferreira RS, da Silva AC, dos Santos TA, Brelaz de Castro MC, Pereira VR, Leite AC. Magalhaes Moreira DR, et al. Among authors: da silva ac. Eur J Med Chem. 2014 Mar 21;75:467-78. doi: 10.1016/j.ejmech.2014.02.001. Epub 2014 Feb 3. Eur J Med Chem. 2014. PMID: 24561675
New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi.
de Moraes Gomes PAT, de Oliveira Barbosa M, Farias Santiago E, de Oliveira Cardoso MV, Capistrano Costa NT, Hernandes MZ, Moreira DRM, da Silva AC, Dos Santos TAR, Pereira VRA, Brayner Dos Santosd FA, do Nascimento Pereira GA, Ferreira RS, Leite ACL. de Moraes Gomes PAT, et al. Among authors: da silva ac. Eur J Med Chem. 2016 Oct 4;121:387-398. doi: 10.1016/j.ejmech.2016.05.050. Epub 2016 May 24. Eur J Med Chem. 2016. PMID: 27295485
Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death.
da Silva EB, Oliveira E Silva DA, Oliveira AR, da Silva Mendes CH, Dos Santos TA, da Silva AC, de Castro MC, Ferreira RS, Moreira DR, Cardoso MV, de Simone CA, Pereira VR, Leite AC. da Silva EB, et al. Among authors: da silva ac, da silva mendes ch. Eur J Med Chem. 2017 Apr 21;130:39-50. doi: 10.1016/j.ejmech.2017.02.026. Epub 2017 Feb 16. Eur J Med Chem. 2017. PMID: 28242550
Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles.
Santiago Ede F, de Oliveira SA, de Oliveira Filho GB, Moreira DR, Gomes PA, da Silva AL, de Barros AF, da Silva AC, Dos Santos TA, Pereira VR, Gonçalves GG, Brayner FA, Alves LC, Wanderley AG, Leite AC. Santiago Ede F, et al. Among authors: da silva ac, da silva al. Antimicrob Agents Chemother. 2014;58(1):352-63. doi: 10.1128/AAC.01900-13. Epub 2013 Oct 28. Antimicrob Agents Chemother. 2014. PMID: 24165185 Free PMC article.
Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition.
Ribeiro AG, Almeida SMV, de Oliveira JF, Souza TRCL, Santos KLD, Albuquerque APB, Nogueira MCBL, Carvalho Junior LB, Moura RO, da Silva AC, Pereira VRA, Castro MCAB, Lima MDCA. Ribeiro AG, et al. Among authors: da silva ac. Eur J Med Chem. 2019 Nov 15;182:111592. doi: 10.1016/j.ejmech.2019.111592. Epub 2019 Aug 6. Eur J Med Chem. 2019. PMID: 31421632
Novel indol-3-yl-thiosemicarbazone derivatives: Obtaining, evaluation of in vitro leishmanicidal activity and ultrastructural studies.
da Silva PR, de Oliveira JF, da Silva AL, Queiroz CM, Feitosa APS, Duarte DMFA, da Silva AC, de Castro MCAB, Pereira VRA, da Silva RMF, Alves LC, Dos Santos FAB, de Lima MDCA. da Silva PR, et al. Among authors: da silva ac, da silva al, da silva rmf. Chem Biol Interact. 2020 Jan 5;315:108899. doi: 10.1016/j.cbi.2019.108899. Epub 2019 Nov 15. Chem Biol Interact. 2020. PMID: 31738906
494 results