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Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.
Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB. Moreira DR, et al. Among authors: pereira vr. ChemMedChem. 2014 Jan;9(1):177-88. doi: 10.1002/cmdc.201300354. Epub 2013 Nov 7. ChemMedChem. 2014. PMID: 24203393
[Hematological and histopathological evaluation of BALB/c and C57BL/6 mice exposed to Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi].
Pereira VR, de Lorena VM, Galvão-da Silva AP, Nakazawa M, da Silva ED, Ferreira AG, Montarroyos U, Coutinho Ede M, Gomes Yde M. Pereira VR, et al. Rev Soc Bras Med Trop. 2003 Nov-Dec;36(6):739-42. doi: 10.1590/s0037-86822003000600016. Rev Soc Bras Med Trop. 2003. PMID: 15049116 Portuguese.
Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.
Moreira DR, Costa SP, Hernandes MZ, Rabello MM, de Oliveira Filho GB, de Melo CM, da Rocha LF, de Simone CA, Ferreira RS, Fradico JR, Meira CS, Guimarães ET, Srivastava RM, Pereira VR, Soares MB, Leite AC. Moreira DR, et al. Among authors: pereira vr. J Med Chem. 2012 Dec 27;55(24):10918-36. doi: 10.1021/jm301518v. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23167554
Sulfonamide-metal complexes endowed with potent anti-Trypanosoma cruzi activity.
Chohan ZH, Hernandes MZ, Sensato FR, Moreira DR, Pereira VR, Neves JK, de Oliveira AP, de Oliveira BC, Leite AC. Chohan ZH, et al. Among authors: pereira vr. J Enzyme Inhib Med Chem. 2014 Apr;29(2):230-6. doi: 10.3109/14756366.2013.766608. Epub 2013 Feb 25. J Enzyme Inhib Med Chem. 2014. PMID: 23432595
Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles.
Santiago Ede F, de Oliveira SA, de Oliveira Filho GB, Moreira DR, Gomes PA, da Silva AL, de Barros AF, da Silva AC, Dos Santos TA, Pereira VR, Gonçalves GG, Brayner FA, Alves LC, Wanderley AG, Leite AC. Santiago Ede F, et al. Among authors: pereira vr. Antimicrob Agents Chemother. 2014;58(1):352-63. doi: 10.1128/AAC.01900-13. Epub 2013 Oct 28. Antimicrob Agents Chemother. 2014. PMID: 24165185 Free PMC article.
Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.
Magalhaes Moreira DR, de Oliveira AD, Teixeira de Moraes Gomes PA, de Simone CA, Villela FS, Ferreira RS, da Silva AC, dos Santos TA, Brelaz de Castro MC, Pereira VR, Leite AC. Magalhaes Moreira DR, et al. Among authors: pereira vr. Eur J Med Chem. 2014 Mar 21;75:467-78. doi: 10.1016/j.ejmech.2014.02.001. Epub 2014 Feb 3. Eur J Med Chem. 2014. PMID: 24561675
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation.
Cardoso MV, de Siqueira LR, da Silva EB, Costa LB, Hernandes MZ, Rabello MM, Ferreira RS, da Cruz LF, Moreira DR, Pereira VR, de Castro MC, Bernhardt PV, Leite AC. Cardoso MV, et al. Among authors: pereira vr. Eur J Med Chem. 2014 Oct 30;86:48-59. doi: 10.1016/j.ejmech.2014.08.012. Epub 2014 Aug 6. Eur J Med Chem. 2014. PMID: 25147146
Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain.
Espíndola JW, Cardoso MV, Filho GB, Oliveira E Silva DA, Moreira DR, Bastos TM, Simone CA, Soares MB, Villela FS, Ferreira RS, Castro MC, Pereira VR, Murta SM, Sales Junior PA, Romanha AJ, Leite AC. Espíndola JW, et al. Among authors: pereira vr. Eur J Med Chem. 2015 Aug 28;101:818-35. doi: 10.1016/j.ejmech.2015.06.048. Epub 2015 Jul 3. Eur J Med Chem. 2015. PMID: 26231082
139 results