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25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.
Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH Jr, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK. Shibata N, et al. Among authors: morello cs. J Biol Chem. 2013 Dec 13;288(50):35812-23. doi: 10.1074/jbc.M113.519637. Epub 2013 Nov 4. J Biol Chem. 2013. PMID: 24189069 Free PMC article.
A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2.
Bernstein DI, Morello CS, Cardin RD, Bravo FJ, Kraynyak KA, Spector DH. Bernstein DI, et al. Among authors: morello cs. Vaccine. 2020 Jan 3;38(1):79-89. doi: 10.1016/j.vaccine.2019.09.090. Epub 2019 Oct 11. Vaccine. 2020. PMID: 31611098
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