Schmid CL - Search Results

1

Development of functionally selective, small molecule agonists at kappa opioid receptors.

Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM. Zhou L, et al. Among authors: schmid cl. J Biol Chem. 2013 Dec 20;288(51):36703-16. doi: 10.1074/jbc.M113.504381. Epub 2013 Nov 1. J Biol Chem. 2013. PMID: 24187130 Free PMC article.

2

Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo.

Schmid CL, Raehal KM, Bohn LM. Schmid CL, et al. Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):1079-84. doi: 10.1073/pnas.0708862105. Epub 2008 Jan 14. Proc Natl Acad Sci U S A. 2008. PMID: 18195357 Free PMC article.

3

Physiological and pharmacological implications of beta-arrestin regulation.

Schmid CL, Bohn LM. Schmid CL, et al. Pharmacol Ther. 2009 Mar;121(3):285-93. doi: 10.1016/j.pharmthera.2008.11.005. Epub 2008 Dec 6. Pharmacol Ther. 2009. PMID: 19100766 Free PMC article. Review.

4

Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6.

Raehal KM, Schmid CL, Medvedev IO, Gainetdinov RR, Premont RT, Bohn LM. Raehal KM, et al. Among authors: schmid cl. Drug Alcohol Depend. 2009 Oct 1;104(3):187-96. doi: 10.1016/j.drugalcdep.2009.04.011. Epub 2009 Jun 3. Drug Alcohol Depend. 2009. PMID: 19497686 Free PMC article.

5

Serotonin receptor signaling and regulation via β-arrestins.

Bohn LM, Schmid CL. Bohn LM, et al. Among authors: schmid cl. Crit Rev Biochem Mol Biol. 2010 Dec;45(6):555-66. doi: 10.3109/10409238.2010.516741. Epub 2010 Oct 7. Crit Rev Biochem Mol Biol. 2010. PMID: 20925600 Free PMC article. Review.

6

Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo.

Schmid CL, Bohn LM. Schmid CL, et al. J Neurosci. 2010 Oct 6;30(40):13513-24. doi: 10.1523/JNEUROSCI.1665-10.2010. J Neurosci. 2010. PMID: 20926677 Free PMC article.

7

Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.

Groer CE, Schmid CL, Jaeger AM, Bohn LM. Groer CE, et al. Among authors: schmid cl. J Biol Chem. 2011 Sep 9;286(36):31731-41. doi: 10.1074/jbc.M111.248310. Epub 2011 Jul 14. J Biol Chem. 2011. PMID: 21757712 Free PMC article.

8

Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.

Raehal KM, Schmid CL, Groer CE, Bohn LM. Raehal KM, et al. Among authors: schmid cl. Pharmacol Rev. 2011 Dec;63(4):1001-19. doi: 10.1124/pr.111.004598. Epub 2011 Aug 26. Pharmacol Rev. 2011. PMID: 21873412 Free PMC article. Review.

9

β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner.

Nguyen PT, Schmid CL, Raehal KM, Selley DE, Bohn LM, Sim-Selley LJ. Nguyen PT, et al. Among authors: schmid cl. Biol Psychiatry. 2012 Apr 15;71(8):714-24. doi: 10.1016/j.biopsych.2011.11.027. Epub 2012 Jan 20. Biol Psychiatry. 2012. PMID: 22264443 Free PMC article.

10

Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons.

Schmid CL, Streicher JM, Groer CE, Munro TA, Zhou L, Bohn LM. Schmid CL, et al. J Biol Chem. 2013 Aug 2;288(31):22387-98. doi: 10.1074/jbc.M113.476234. Epub 2013 Jun 17. J Biol Chem. 2013. PMID: 23775075 Free PMC article.

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