Hodder P - Search Results

1

Development of functionally selective, small molecule agonists at kappa opioid receptors.

Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM. Zhou L, et al. Among authors: hodder p. J Biol Chem. 2013 Dec 20;288(51):36703-16. doi: 10.1074/jbc.M113.504381. Epub 2013 Nov 1. J Biol Chem. 2013. PMID: 24187130 Free PMC article.

2

Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening.

Madoux F, Li X, Chase P, Zastrow G, Cameron MD, Conkright JJ, Griffin PR, Thacher S, Hodder P. Madoux F, et al. Among authors: hodder p. Mol Pharmacol. 2008 Jun;73(6):1776-84. doi: 10.1124/mol.108.045963. Epub 2008 Mar 11. Mol Pharmacol. 2008. PMID: 18334597 Free PMC article.

3

Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds.

Roth J, Madoux F, Hodder P, Roush WR. Roth J, et al. Among authors: hodder p. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2628-32. doi: 10.1016/j.bmcl.2008.03.027. Epub 2008 Mar 14. Bioorg Med Chem Lett. 2008. PMID: 18374567 Free PMC article.

4

Inhibition of adrenocortical carcinoma cell proliferation by steroidogenic factor-1 inverse agonists.

Doghman M, Cazareth J, Douguet D, Madoux F, Hodder P, Lalli E. Doghman M, et al. Among authors: hodder p. J Clin Endocrinol Metab. 2009 Jun;94(6):2178-83. doi: 10.1210/jc.2008-2163. Epub 2009 Mar 24. J Clin Endocrinol Metab. 2009. PMID: 19318454 Free PMC article.

5

Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening.

Brothers SP, Saldanha SA, Spicer TP, Cameron M, Mercer BA, Chase P, McDonald P, Wahlestedt C, Hodder PS. Brothers SP, et al. Among authors: hodder ps. Mol Pharmacol. 2010 Jan;77(1):46-57. doi: 10.1124/mol.109.058677. Epub 2009 Oct 16. Mol Pharmacol. 2010. PMID: 19837904 Free PMC article.

6

An ultra-high throughput cell-based screen for wee1 degradation inhibitors.

Madoux F, Simanski S, Chase P, Mishra JK, Roush WR, Ayad NG, Hodder P. Madoux F, et al. Among authors: hodder p. J Biomol Screen. 2010 Sep;15(8):907-17. doi: 10.1177/1087057110375848. Epub 2010 Jul 26. J Biomol Screen. 2010. PMID: 20660794 Free PMC article.

7

Identification and characterization of steroidogenic factor-1 inverse agonists.

Doghman M, Madoux F, Hodder P, Lalli E. Doghman M, et al. Among authors: hodder p. Methods Enzymol. 2010;485:3-23. doi: 10.1016/B978-0-12-381296-4.00001-4. Methods Enzymol. 2010. PMID: 21050908

8

Small-molecule proteostasis regulators for protein conformational diseases.

Calamini B, Silva MC, Madoux F, Hutt DM, Khanna S, Chalfant MA, Saldanha SA, Hodder P, Tait BD, Garza D, Balch WE, Morimoto RI. Calamini B, et al. Among authors: hodder p. Nat Chem Biol. 2011 Dec 25;8(2):185-96. doi: 10.1038/nchembio.763. Nat Chem Biol. 2011. PMID: 22198733 Free PMC article.

9

In pursuit of synthetic modulators for the orphan retina-specific nuclear receptor NR2E3.

Qin Q, Knapinska A, Dobri N, Madoux F, Chase P, Hodder P, Petrukhin K. Qin Q, et al. Among authors: hodder p. J Ocul Pharmacol Ther. 2013 Apr;29(3):298-309. doi: 10.1089/jop.2012.0135. Epub 2012 Oct 25. J Ocul Pharmacol Ther. 2013. PMID: 23098562 Free PMC article.

10

Inhibiting AMPylation: a novel screen to identify the first small molecule inhibitors of protein AMPylation.

Lewallen DM, Sreelatha A, Dharmarajan V, Madoux F, Chase P, Griffin PR, Orth K, Hodder P, Thompson PR. Lewallen DM, et al. Among authors: hodder p. ACS Chem Biol. 2014 Feb 21;9(2):433-42. doi: 10.1021/cb4006886. Epub 2013 Nov 25. ACS Chem Biol. 2014. PMID: 24274060 Free PMC article.

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