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Development of functionally selective, small molecule agonists at kappa opioid receptors.
Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM. Zhou L, et al. Among authors: cameron md. J Biol Chem. 2013 Dec 20;288(51):36703-16. doi: 10.1074/jbc.M113.504381. Epub 2013 Nov 1. J Biol Chem. 2013. PMID: 24187130 Free PMC article.
Synthesis and SAR of tetrahydroisoquinolines as Rev-erbα agonists.
Noel R, Song X, Shin Y, Banerjee S, Kojetin D, Lin L, Ruiz CH, Cameron MD, Burris TP, Kamenecka TM. Noel R, et al. Among authors: cameron md. Bioorg Med Chem Lett. 2012 Jun 1;22(11):3739-42. doi: 10.1016/j.bmcl.2012.04.023. Epub 2012 Apr 13. Bioorg Med Chem Lett. 2012. PMID: 22560469 Free PMC article.
Small molecule amides as potent ROR-γ selective modulators.
Khan PM, El-Gendy Bel-D, Kumar N, Garcia-Ordonez R, Lin L, Ruiz CH, Cameron MD, Griffin PR, Kamenecka TM. Khan PM, et al. Among authors: cameron md. Bioorg Med Chem Lett. 2013 Jan 15;23(2):532-6. doi: 10.1016/j.bmcl.2012.11.025. Epub 2012 Nov 22. Bioorg Med Chem Lett. 2013. PMID: 23232056 Free PMC article.
Selective Targeting of Extracellular Insulin-Degrading Enzyme by Quasi-Irreversible Thiol-Modifying Inhibitors.
Abdul-Hay SO, Bannister TD, Wang H, Cameron MD, Caulfield TR, Masson A, Bertrand J, Howard EA, McGuire MP, Crisafulli U, Rosenberry TR, Topper CL, Thompson CR, Schürer SC, Madoux F, Hodder P, Leissring MA. Abdul-Hay SO, et al. Among authors: cameron md. ACS Chem Biol. 2015 Dec 18;10(12):2716-24. doi: 10.1021/acschembio.5b00334. Epub 2015 Sep 30. ACS Chem Biol. 2015. PMID: 26398879 Free PMC article.
161 results