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HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome.
Hermida N, Markl A, Hamelet J, Van Assche T, Vanderper A, Herijgers P, van Bilsen M, Hilfiker-Kleiner D, Noppe G, Beauloye C, Horman S, Balligand JL. Hermida N, et al. Among authors: horman s. Cardiovasc Res. 2013 Jul 1;99(1):44-54. doi: 10.1093/cvr/cvt070. Epub 2013 Mar 29. Cardiovasc Res. 2013. PMID: 23542580
Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.
de Meester C, Timmermans AD, Balteau M, Ginion A, Roelants V, Noppe G, Porporato PE, Sonveaux P, Viollet B, Sakamoto K, Feron O, Horman S, Vanoverschelde JL, Beauloye C, Bertrand L. de Meester C, et al. Among authors: horman s. Cardiovasc Res. 2014 Jan 1;101(1):20-9. doi: 10.1093/cvr/cvt227. Epub 2013 Oct 8. Cardiovasc Res. 2014. PMID: 24104879
The Ca(2+) /calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets.
Onselaer MB, Oury C, Hunter RW, Eeckhoudt S, Barile N, Lecut C, Morel N, Viollet B, Jacquet LM, Bertrand L, Sakamoto K, Vanoverschelde JL, Beauloye C, Horman S. Onselaer MB, et al. Among authors: horman s. J Thromb Haemost. 2014 Jun;12(6):973-86. doi: 10.1111/jth.12568. J Thromb Haemost. 2014. PMID: 24655923 Free article.
Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKα1.
Noppe G, Dufeys C, Buchlin P, Marquet N, Castanares-Zapatero D, Balteau M, Hermida N, Bouzin C, Esfahani H, Viollet B, Bertrand L, Balligand JL, Vanoverschelde JL, Beauloye C, Horman S. Noppe G, et al. Among authors: horman s. J Mol Cell Cardiol. 2014 Sep;74:32-43. doi: 10.1016/j.yjmcc.2014.04.018. Epub 2014 May 5. J Mol Cell Cardiol. 2014. PMID: 24805196
AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation.
Gélinas R, Mailleux F, Dontaine J, Bultot L, Demeulder B, Ginion A, Daskalopoulos EP, Esfahani H, Dubois-Deruy E, Lauzier B, Gauthier C, Olson AK, Bouchard B, Des Rosiers C, Viollet B, Sakamoto K, Balligand JL, Vanoverschelde JL, Beauloye C, Horman S, Bertrand L. Gélinas R, et al. Among authors: horman s. Nat Commun. 2018 Jan 25;9(1):374. doi: 10.1038/s41467-017-02795-4. Nat Commun. 2018. PMID: 29371602 Free PMC article.
123 results