Baek DJ - Search Results

1

Structure-activity relationships and molecular modeling of sphingosine kinase inhibitors.

Baek DJ, MacRitchie N, Anthony NG, Mackay SP, Pyne S, Pyne NJ, Bittman R. Baek DJ, et al. J Med Chem. 2013 Nov 27;56(22):9310-27. doi: 10.1021/jm401399c. Epub 2013 Nov 14. J Med Chem. 2013. PMID: 24164513 Free PMC article.

2

Synthesis of selective inhibitors of sphingosine kinase 1.

Baek DJ, MacRitchie N, Pyne NJ, Pyne S, Bittman R. Baek DJ, et al. Chem Commun (Camb). 2013 Mar 14;49(21):2136-8. doi: 10.1039/c3cc00181d. Epub 2013 Feb 7. Chem Commun (Camb). 2013. PMID: 23388656 Free PMC article.

3

Synthesis of cholesterol analogs having varying length alkyl side chains including cholesterol-23, 23, 24, 24, 25, 26, 26, 26, 27, 27, 27-d(11) as probes of cholesterol's functions and properties.

Baek DJ, Bittman R. Baek DJ, et al. Chem Phys Lipids. 2013 Oct-Nov;175-176:99-104. doi: 10.1016/j.chemphyslip.2013.08.003. Epub 2013 Sep 3. Chem Phys Lipids. 2013. PMID: 24012903

4

Cholesterol's aliphatic side chain modulates membrane properties.

Scheidt HA, Meyer T, Nikolaus J, Baek DJ, Haralampiev I, Thomas L, Bittman R, Müller P, Herrmann A, Huster D. Scheidt HA, et al. Among authors: baek dj. Angew Chem Int Ed Engl. 2013 Dec 2;52(49):12848-51. doi: 10.1002/anie.201306753. Epub 2013 Nov 25. Angew Chem Int Ed Engl. 2013. PMID: 24382636 Free PMC article.

5

Membrane properties of cholesterol analogs with an unbranched aliphatic side chain.

Meyer T, Baek DJ, Bittman R, Haralampiev I, Müller P, Herrmann A, Huster D, Scheidt HA. Meyer T, et al. Among authors: baek dj. Chem Phys Lipids. 2014 Dec;184:1-6. doi: 10.1016/j.chemphyslip.2014.08.002. Epub 2014 Aug 27. Chem Phys Lipids. 2014. PMID: 25173446

6

Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics.

Woodcock JM, Coolen C, Goodwin KL, Baek DJ, Bittman R, Samuel MS, Pitson SM, Lopez AF. Woodcock JM, et al. Among authors: baek dj. Oncotarget. 2015 Jun 10;6(16):14522-36. doi: 10.18632/oncotarget.3995. Oncotarget. 2015. PMID: 25971334 Free PMC article.

7

Structure and dynamics of the aliphatic cholesterol side chain in membranes as studied by (2)H NMR spectroscopy and molecular dynamics simulation.

Vogel A, Scheidt HA, Baek DJ, Bittman R, Huster D. Vogel A, et al. Among authors: baek dj. Phys Chem Chem Phys. 2016 Feb 7;18(5):3730-8. doi: 10.1039/c5cp05084g. Phys Chem Chem Phys. 2016. PMID: 26762541

8

Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier.

Wang X, Maruvada R, Morris AJ, Liu JO, Wolfgang MJ, Baek DJ, Bittman R, Kim KS. Wang X, et al. Among authors: baek dj. PLoS Pathog. 2016 Oct 6;12(10):e1005926. doi: 10.1371/journal.ppat.1005926. eCollection 2016 Oct. PLoS Pathog. 2016. PMID: 27711202 Free PMC article.

9

Synthesis of dansyl labeled sphingosine kinase 1 inhibitor.

Park EY, Lee T, Oh YS, Lee JY, Shrestha J, Hong SW, Jin YJ, Jo G, Kim S, Hwang GT, Han DS, Baek DJ. Park EY, et al. Among authors: baek dj. Chem Phys Lipids. 2018 Sep;215:29-33. doi: 10.1016/j.chemphyslip.2018.07.005. Epub 2018 Jul 22. Chem Phys Lipids. 2018. PMID: 30044952

10

Verification of the Necessity of the Tolyl Group of PF-543 for Sphingosine Kinase 1 Inhibitory Activity.

Kim SB, Lee T, Moon HS, Ki SH, Oh YS, Lee JY, Kim SB, Park JE, Kwon Y, Kim S, Baek DJ, Park EY. Kim SB, et al. Among authors: baek dj. Molecules. 2020 May 27;25(11):2484. doi: 10.3390/molecules25112484. Molecules. 2020. PMID: 32471162 Free PMC article.

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